Docetax Rtu 120mg Injection contains Docetaxel, a chemotherapy drug from the taxane family. By disrupting cell division more precisely, by stabilizing microtubules- it is used to treat a variety of malignancies by stopping the division and multiplication of cancer cells.

Brand Name: Docetax Rtu

Composition: Docetaxel

Mechanism of Action:

By encouraging the formation of microtubules from tubulin dimers and preventing their disintegration, docetaxel functions. By stabilizing the microtubules and restricting their normal activity during mitosis, or cell division, this stops cancer cells from growing and spreading and ultimately results in cell death.

Uses:

• Breast Cancer
• Non-Small Cell Lung Cancer (NSCLC)
• Prostate Cancer
• Gastric Cancer
• Head and Neck Cancer

Dosage and Administration:

The type of cancer being treated and the course of treatment affect the dosage of docetaxel, which is typically determined by the patient's body surface area (BSA). given as an infusion using an intravenous (IV).

Side Effects:

• Fatigue
• Weakness
• Hair loss
• Skin rash
• Swelling
• Nausea
• Vomiting
• Muscle pain
• Mouth sores
• Diarrhea

Safety Advise:

Liver  

Patients with hepatic impairment may require dose modifications. Throughout treatment, liver function should be routinely assessed. Kindly speak with your healthcare provider.

Kidney  

Patients with renal impairment may require dose modifications. Throughout treatment, kidney function should be routinely assessed. Kindly speak with your healthcare provider.

Pregnancy  

As docetaxel may harm the fetus, it is not advised to use it during pregnancy. Kindly speak with your healthcare provider.

Breast Feeding  

Docetax 120mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby. Kindly speak with your healthcare provider.

Alcohol  

Drinking alcohol while taking Docetax 120mg Injection is not advised. Kindly speak with your healthcare provider.

Storage:

Store the vial at 2°C to 8°C (36°F to 46°F) in a refrigerator. Do not freeze. Protect from light.

How to use this Medication?

This medication is administered intravenously. A medical expert with specialized training administers it in a hospital or clinic.

Consult your pediatrician about this medication's use in kids. Extra caution could be required.

References:

1.     Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs. 2005 Dec;65:2513-31.

2.     Clarke SJ, Rivory LP. Clinical pharmacokinetics of docetaxel. Clinical pharmacokinetics. 1999 Feb;36:99-114.

3.     Montero A, Fossella F, Hortobagyi G, Valero V. Docetaxel for treatment of solid tumours: a systematic review of clinical data. The lancet oncology. 2005 Apr 1;6(4):229-39.

4.   Pienta KJ. Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer. InSeminars in oncology 2001 Aug 1 (Vol. 28, pp. 3-7). WB Saunders.

Disclaimer:

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Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India