Bevatas 400mg Injection

Bevatas 400mg Injection contains Bevacizumab, a monoclonal antibody used in cancer therapy. It functions by preventing angiogenesis, which is how cancers create their own blood supply.

Brand Name: Bevatas

Composition: Bevacizumab

Mechanism of Action:

It seeks out and attaches itself to vascular endothelial growth factor (VEGF), a protein that stimulates blood vessel development. Bevacizumab stops VEGF from attaching to its receptors on endothelial cells, which stops new blood vessels from forming and stops tumor development and metastasis.

Uses:

• Metastatic Colorectal Cancer
• Non-Small Cell Lung Cancer
• Breast Cancer
• Glioblastoma
• Ovarian Cancer
• Cervical Cancer

Dosage and Administration:

Depending on the particular malignancy being treated and the patient's general health, the dosage may change. A gradual intravenous infusion of bevacizumab is administered; the infusion rate can be changed according to the patient's tolerance.

Side Effects:

• Hypertension
• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Fever
• Dizziness
• Increased risk of bleeding

Safety Advise:

Liver  

Caution is advised in patients with hepatic impairment, and dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Kidney  

Caution is advised in patients with renal impairment, and dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Pregnancy  

It should only be used if absolutely necessary because its safety during pregnancy has not been thoroughly demonstrated. Kindly speak with your healthcare provider.

Breast Feeding  

Using Bevatas Injection while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Alcohol  

Alcohol consumption while using Bevatas Injection is not advised. Kindly speak with your healthcare provider.

Storage:

Bevatas Injection should be kept out of direct sunlight and at room temperature, between 20°C and 25°C.

How to use this Medication?

Usually given once every two or three weeks, bevacizumab injection is a liquid that a medical expert administers slowly into a vein. The dosage schedule is customized based on your individual condition and response to treatment.

When the drug is infused, bevacizumab injectable products have the potential to induce severe side effects. Notify your doctor right once if you suffer from any of the following symptoms: headaches, dizziness, chest discomfort, flushing, itching, rash, hives, chills, shaking, sweating, or shortness of breath. If you have these or other side effects, your doctor might need to reduce the rate of your infusion or postpone or terminate your treatment.

References:

1.      Kazazi-Hyseni F, Beijnen JH, Schellens JH. Bevacizumab. The oncologist. 2010 Aug;15(8):819.

2.      Braghiroli MI, Sabbaga J, Hoff PM. Bevacizumab: overview of the literature. Expert review of anticancer therapy. 2012 May 1;12(5):567-80.

3.      Bakri SJ, Snyder MR, Reid JM, Pulido JS, Singh RJ. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology. 2007 May 1;114(5):855-9.

4.      Keating GM. Bevacizumab: a review of its use in advanced cancer. Drugs. 2014 Oct;74(16):1891-925.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

Frequently Asked Questions (FAQs):

1. What is Bevatas 400mg Injection?

Bevatas 400mg contains Bevacizumab, an angiogenesis inhibitor (targeted therapy). It may be prescribed for the treatment of various advanced cancers. Strict adherence to an oncologist's oversight is required.

2. How may Bevatas work?

It is believed to bind to VEGF, a protein that stimulates blood vessel formation. By potentially cutting off the blood supply to the tumour, it may slow down cancer growth.

3. What conditions may it be prescribed for?

It may be considered for metastatic colorectal cancer, non-small cell lung cancer, glioblastoma, and certain ovarian or cervical cancers, strictly based on a doctor's diagnosis.

4. How is it administered?

It is administered as an intravenous (IV) infusion by a healthcare professional in a hospital. You must adhere to the clinical appointments scheduled for your infusions.

5. How often is the infusion given?

Depending on the specific cancer protocol, it may typically be given once every 2 or 3 weeks. The oncology team will strictly adhere to the calculated schedule.

6. What are the possible side effects?

Patients may potentially experience nosebleeds, high blood pressure, protein in the urine, fatigue, or headache. Report these to your doctor.

7. Are there serious cardiovascular or bleeding risks?

Yes, it may potentially cause severe bleeding, gastrointestinal perforation, or arterial blood clots. Doctors will mandate strict adherence to safety monitoring during therapy.

8. Does it require regular blood pressure monitoring?

Because it frequently raises blood pressure, you must adhere strictly to your doctor's instructions for monitoring and managing your blood pressure.

9. How does it affect wound healing?

It may potentially impair wound healing. You must adhere to your doctor's instructions to suspend treatment prior to any planned elective surgeries.

10. Can it be used with chemotherapy?

Yes, it is frequently used in combination with chemotherapy regimens, as determined by an oncologist's evidence-based protocol.

11. Is it safe during pregnancy?

It may cause fetal harm. Strict adherence to effective contraception during and for a period after treatment is required, as advised by your physician.

12. Is Bevatas a prescription medicine?

Yes, it is a prescription-only oncology infusion.

Medical Disclaimer:

Bevatas 400mg Injection is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.