Cacit 500mg Tablet containing Capecitabine is an oral chemotherapy medication primarily used to treat certain types of cancer.

Brand Name: Cacit

Composition: Capecitabine

Mechanism of Action:

The body transforms the prodrug capecitabine into 5-fluorouracil (5-FU). 5-FU is an antimetabolite that prevents the growth of cancer cells by interfering with DNA synthesis and RNA processing.

Uses:

• Colorectal cancer
• Breast cancer

Dosage and Administration:

The dosage of Capecitabine varies depending on the type of cancer, the treatment regimen, and the patient’s body surface area.

Side Effects:

• Diarrhea
• Nausea
• Vomiting
• Fatigue
• Hair loss
• Constipation
• Dehydration
• Pain
• Fever
• Edema
• Hand-foot syndrome
• Mouth sores
• Dizziness
• Anemia

Safety Advise:

Liver  

Close observation and dose modifications may be necessary for patients with liver impairment. Kindly speak with your healthcare provider.

Kidnay  

Close observation and dose modifications may be necessary for patients with renal impairment. Kindly speak with your healthcare provider.

Pregnancy  

Capecitabine should not be used during pregnancy since it may harm the fetus. Kindly speak with your healthcare provider.

Breast Feeding  

Using a 500 mg tablet of Cacit during nursing is not advised. Evidence points to the drug's potential to be hazardous to the unborn child. Kindly speak with your healthcare provider.

Alcohol  

The safety of combining alcohol with Cacit 500mg Tablets is unknown. Kindly speak with your healthcare provider.

Storage:

Store at room temperature, typically between 15°C and 30°C (59°F and 86°F). Keep in a dry place, protected from light and humidity.

How to use this Medication?

Capecitabine is taken orally as a pill, typically twice daily after meals, for two weeks. The next cycle is then started after a one-week respite. Your doctor will decide how frequently to repeat the cycle based on your reaction and any adverse effects. It should be taken with a glass of water at approximately the same time every day. Pay close attention to the instructions on your prescription, and ask your doctor or pharmacist any questions you may have.

Do not break, chew, or crush the tablets; instead, swallow them whole.

References:

1.      Walko CM, Lindley C. Capecitabine: a review. Clinical therapeutics. 2005 Jan 1;27(1):23-44.

2.      Mikhail SE, Sun JF, Marshall JL. Safety of capecitabine: a review. Expert opinion on drug safety. 2010 Sep 1;9(5):831-41.

3.   Saif MW, Katirtzoglou NA, Syrigos KN. Capecitabine: an overview of the side effects and their management. Anti-cancer drugs. 2008 Jun 1;19(5):447-64.

4.      Ishitsuka H. Capecitabine: preclinical pharmacology studies. Investigational new drugs. 2000 Nov;18:343-54.

5.    Wagstaff AJ, Ibbotson T, Goa KL. Capecitabine: a review of its pharmacology and therapeutic efficacy in the management of advanced breast cancer. Drugs. 2003 Jan;63:217-36.

Disclaimer:

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Marketer details

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Country of origin: India