Erypeg 75mcg Injection is a pegylated recombinant human erythropoietin injection that is primarily used to treat anemia associated with chronic kidney disease (CKD), cancer chemotherapy, and other conditions that cause low red blood cell counts.

Brand Name: Erypeg

Composition: Pegylated Recombinant Human Erythropoietin

Mechanism of Action:

The kidneys naturally create erythropoietin, a hormone that controls the synthesis of red blood cells. The synthetic version of this hormone found in Erypeg 30 is pegylated, or bound to polyethylene glycol, to prolong its half-life in the blood. Compared to non-pegylated forms of erythropoietin, the pegylation increases stability and duration of effect, requiring fewer doses.

Uses:

Anemia in Chronic Kidney Disease 

Anemia Due to Chemotherapy

Anemia in HIV-Infected Patients

Dosage and Administration:

Erypeg 75 is often injected subcutaneously, or behind the skin, in the upper arm, thigh, or abdomen. The patient's weight, the underlying reason of their anemia, and their response to treatment all influence the precise dosage.

Side Effects:

·         Injection Site Reactions

·         Headache

·         Nausea

·         Fever

·         Vomiting

·         Joint Pain

·         Chills

·         Cough

·         High Blood Pressure

·         Dizziness

·         Weight Loss

·         Insomnia

Safety Advise:

Liver  

Patients with liver illness should use Erypeg Injection with caution. Erypeg Injection dosage adjustments might be required. Kindly speak with your healthcare provider.

Kidney  

Patients with renal illness should use Erypeg Injection with caution. Erypeg Injection dosage adjustments might be required. Kindly speak with your healthcare provider.

Pregnancy  

Animal studies suggest that Erypeg injection could be harmful to the fetus, so it may not be safe to use during pregnancy. Before using it, discuss benefits and risks with your healthcare provider.

Breast Feeding  

Using Erypeg Injection while nursing is most likely dangerous. The medication may damage the developing baby if it enters the breastmilk, according to limited human data. Kindly speak with your healthcare provider.

Alcohol  

It is unknown if drinking alcohol while using Erypeg Injection is safe. Kindly speak with your healthcare provider.

Driving  

You may get adverse reactions from Erypeg Injection that might affect your driving. Kindly speak with your healthcare provider.

Storage:

Store in the refrigerator at 2°C to 8°C. Do not freeze it. Protect it from light and keep it out of reach of children.

References:

1.  Cao X, Chen Z, Yu Z, Ge Y, Zeng X. Pharmacokinetics of PEGylated recombinant human erythropoietin in rats. Journal of analytical methods in chemistry. 2014;2014(1):918686.

2.  Van Maerken T, Dhondt A, Delanghe JR. A rapid and simple assay to determine pegylated erythropoietin in human serum. Journal of Applied Physiology. 2010 Apr;108(4):800-3.

Disclaimer:

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Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India