Clexane 40mg Injection

Clexane 40mg Injection contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) that is used as an anticoagulant to prevent and treat blood clots. It is frequently used in a variety of illnesses that call for blood thinning and can lower the risk of pulmonary embolism (PE) and deep vein thrombosis (DVT).

Brand Name: Clexane

Composition: Enoxaparin Sodium

Mechanism of Action:

Blood clots are prevented by enoxaparin-induced enhancement of antithrombin III's activity, which inhibits Factor Xa and Factor IIa (thrombin). Compared to thrombin, Factor Xa is more impacted by it.

Uses:

• Deep Vein Thrombosis
• Pulmonary Embolism.
• Blood Clot Prevention in Dialysis

Dosage and Administration:

Enoxaparin is injected subcutaneously, usually in the abdomen; the dosage is determined by the indication. Once injection is complete, avoid rubbing the injection site.

Side Effects:

• Bleeding
• Injection site reactions (bruising, pain, redness)
• Thrombocytopenia
• Elevated liver enzymes
• Spinal/epidural hematomas
• Headache
• Fever
• Diarrhea

Safety Advise:

Kidney

Patients with kidney illness should use clexane injection with caution. Clexane injection dosage adjustments can be required. Kindly speak with your healthcare provider.

Liver

The use of clexane injection in individuals with liver dysfunction is not well-documented. Kindly speak with your healthcare provider.

Pregnancy

Prior to beginning the 40mg injection of clexane medication, let your healthcare provider know if you are pregnant, suspect you are pregnant, or are planning to become pregnant. 

Breast Feeding

It is strongly recommended that you speak with your healthcare provider before using an injection of clexane 40mg if you are nursing a baby.

Alcohol

It is unknown if drinking alcohol while using an injection of clexane is safe. Kindly speak with your healthcare provider.

Storage:

Store the injection at a temperature between 15°C to 25°C (room temperature). Protection: Keep the injection away from light and moisture.

How to use this medication?

Enoxaparin is injected subcutaneously (under the skin), typically twice a day for 10-14 days. Follow your doctor's instructions exactly, and do not adjust the dose or frequency on your own.

Use enoxaparin as prescribed even if you feel good. enoxaparin should not be stopped without first consulting your doctor.

References:

1.    Casele HL, Laifer SA, Woelkers DA, Venkataramanan R. Changes in the pharmacokinetics of the low-molecular-weight heparin enoxaparin sodium during pregnancy. American journal of obstetrics and gynecology. 1999 Nov 1;181(5):1113-7.

2.     Saltissi D, Morgan C, Westhuyzen J, Healy H. Comparison of low-molecular-weight heparin (enoxaparin sodium) and standard unfractionated heparin for haemodialysis anticoagulation. Nephrology Dialysis Transplantation. 1999 Nov 1;14(11):2698-703.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Name: Sanofi India Ltd

Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Country of origin: France

Frequently Asked Questions (FAQs):

1. What is Clexane 40mg Injection? 

Clexane 40mg contains Enoxaparin, a widely used low molecular weight heparin. It may be prescribed as an anticoagulant, requiring strict adherence to a physician's dosing schedule.

2. How may Clexane work?

It is believed to target and inhibit specific coagulation factors, which may potentially stop the blood from clotting inappropriately inside blood vessels.

3. What conditions may it be indicated for?

It may be considered for the treatment of deep vein thrombosis (DVT), pulmonary embolism, and certain acute coronary syndromes, based on a doctor's diagnosis.

4. How is Clexane administered?

It is typically given as a subcutaneous injection in the abdominal area. Patients must strictly adhere to the administration instructions provided by their healthcare team.

5. What is the usual dosage?

The 40mg dose is often used in a weight-based treatment regimen. You must follow your doctor's prescribed regimen exactly and never adjust the dose yourself.

6. What are the possible side effects?

Patients may potentially experience bruising or pain at the injection site, minor bleeding from the gums, or elevated liver enzymes.

7. What signs may indicate serious bleeding?

Unusual or severe bruising, blood in the stool or urine, or coughing up blood requires immediate medical attention and adherence to emergency protocols.

8. May it be used during pregnancy?

It may be considered as an anticoagulant during pregnancy under strict obstetric supervision, as it does not cross the placenta.

9. What monitoring may be required?

Your doctor may potentially advise periodic platelet count checks. You must attend these check-ups to monitor for safe continued use.

10. What if I am having surgery or dental work?

You must inform your surgeon or dentist that you are taking Clexane, as they will need to strictly adhere to protocols for managing bleeding risks during procedures.

11. Are there drug interactions?

Using it with other blood thinners, aspirin, or NSAIDs may potentially increase bleeding risk. Adhere to your doctor's approved medication list.

12. Is Clexane a prescription medicine?

Yes. It is a prescription-only injectable anticoagulant.

Medical Disclaimer:

Clexane 40mg Injection is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.