Amfight 50mg Injection contains Amphotericin B, by breaking down fungal cell membranes, used to treat leishmaniasis and serious fungal infections. 

Brand Name: Amfight

Composition: Amphotericin B

Mechanism of Action:

One of the main components of fungal cell membranes, ergosterol, is bound by liposomal amphotericin B. Cell death results from this binding's disruption of the membrane's integrity. Improved medication distribution to the infection site is made possible by the liposomal formulation, which also reduces toxicity to human cells—especially the kidneys.

Uses:

Fungal Infections: Particularly effective in treating invasive fungal infections, including:

·        Aspergillosis

·        Candidiasis

·        Cryptococcosis

·        Mucormycosis

Side effects:

• Fever
• Chills
• Nausea
• Vomiting
• Headache
• Dizziness
• Diarrhea
• Infusion-related reactions (e.g., dyspnea)
• Electrolyte imbalances (e.g., hypokalemia)
• Anaphylactic reactions

Dosage and Administration:

Administrated through intravenous route, to lower the chance of infusion-related reactions, infusion rates should be monitored carefully. The kind and severity of the infection may affect the dose. Dose may differ; usually, it is modified in accordance with patient tolerance and the clinical response.

Safety Advise:

Lungs  

The safety of Amfight Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Amfight Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Amfight Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Amfight should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Amfight while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Storage:

Keep the product at room temperature; the recommended range is 20°C to 25°. Store away from moisture and in a dry environment. Keep out of direct sunlight and keep in original packaging. Keep out of children grasp.

How to use this Medication?

When used intravenously, amphotericin B liposomal injection is usually given once daily or on designated days to treat the disease. Reactions can occur one to three hours after infusion, particularly with beginning dosages. If you have symptoms during treatment, such as a fever, chills, chest discomfort, or trouble breathing, let your doctor know right away.

References:

1.     Lemke A, Kiderlen AF, Kayser O. Amphotericin b. Applied microbiology and biotechnology. 2005 Aug;68:151-62.

2.     Ellis D. Amphotericin B: spectrum and resistance. Journal of Antimicrobial Chemotherapy. 2002 Jan 1;49(suppl_1):7-10.

3.     Hamill RJ. Amphotericin B formulations: a comparative review of efficacy and toxicity. Drugs. 2013 Jun;73:919-34.

4.     Laniado-Laborín R, Cabrales-Vargas MN. Amphotericin B: side effects and toxicity. Revista iberoamericana de micología. 2009 Oct 1;26(4):223-7.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Celon Laboratories Ltd

Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Country of origin: India