Rybelsus 14mg Tablet contains Semaglutide, a medication used primarily to manage type 2 diabetes mellitus. It is a member of the group of medications called GLP-1 receptor agonists.

Brand Name: Rybelsus

Composition: Semaglutide

Mechanism of Action:

The GLP-1 hormone, which is essential for controlling blood glucose levels, is mimicked by semaglutide. When blood sugar levels are high, it increases insulin secretion by inducing the pancreas to release more insulin. Semaglutide also inhibits the liver's production of glucagon, a hormone that causes blood sugar levels to rise. Additionally, it slows down the rate at which food exits the stomach by delaying gastric emptying, which helps curb appetite and manage post-meal glucose increases.

Uses:

Type 2 Diabetes Mellitus

Dosage and Administration:

To lessen gastrointestinal side effects, Rybelsus is often begun at 3 mg once day for the first month before being increased to 7 mg daily. Taken orally once a day with a little water on an empty stomach

 Side Effects:

• Headache
• Nausea
• Fever
• Vomiting
• Joint Pain
• Abdominal pain
• Constipation
• Chills
• Cough
• High Blood Pressure
• Dizziness
• Weight Loss
• Insomnia

Safety Advise:

Liver  

Patients with liver illness should use Rybelsus with caution. Rybelsus dosage adjustments might be required. Kindly speak with your healthcare provider.

Kidney  

Patients with renal illness should use Rybelsus with caution. Rybelsus dosage adjustments might be required. Kindly speak with your healthcare provider.

Pregnancy    

Animal studies suggest that Rybelsus could be harmful to the fetus, so it may not be safe to use during pregnancy. Before using it, discuss benefits and risks with your healthcare provider.

Breast Feeding  

Using Rybelsus while nursing is most likely dangerous. The medication may damage the developing baby if it enters the breastmilk, according to limited human data. Kindly speak with your healthcare provider.

Alcohol  

It is unknown if drinking alcohol while using Rybelsus is unsafe. Kindly speak with your healthcare provider.

Storage:

Store at room temperature, between 20°C and 25°C (68°F to 77°F).  Keep in the original packaging to protect from moisture and light.

How to use this Medication?

As prescribed, take this medication orally at the same time each day, right after waking up, and with no more than four ounces of plain water. After ingesting the tablets whole, wait at least half an hour before eating, drinking, or taking any other drugs.

With every prescription and refill, the pharmacist will provide you with a unique MedGuide. Every time, make sure to carefully read this information.

 

Discuss the usage of this drug in children with your care team. Extra caution could be required.

References:

1.      Smits MM, Van Raalte DH. Safety of semaglutide. Frontiers in endocrinology. 2021 Jul 7;12:645563.

2.      Chao AM, Tronieri JS, Amaro A, Wadden TA. Semaglutide for the treatment of obesity. Trends in cardiovascular medicine. 2023 Apr 1;33(3):159-66.

3.    Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S, Hardt-Lindberg S, Hovingh GK, Kahn SE, Kushner RF, Lingvay I. Semaglutide and cardiovascular outcomes in obesity without diabetes. New England Journal of Medicine. 2023 Dec 14;389(24):2221-32.

4.     Wilding JP, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MT, Wadden TA, Wharton S. Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine. 2021 Mar 18;384(11):989-1002.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

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