Tafnat 25mg Tablet

Tafnat 25mg Tablet contains Tenofovir Alafenamide, which belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs). It is mostly used to treat chronic hepatitis B infection and HIV (Human Immunodeficiency Virus) infection.

Brand Name: Tafnat

Composition: Tenofovir Alafenamide

Mechanism of Action:

Tenofovir diphosphate, the active form of tenofovir alafenamide, is produced inside the cells and inhibits the reverse transcriptase enzyme in both HIV and HBV. This slows the evolution of the disease and improves liver function (in the case of hepatitis B) by stopping the virus from growing and lowering the viral load in the blood.

Uses:

HIV Infection

Chronic Hepatitis B Infection

Dosage and Administration:

One tablet taken once a day, with or without food, is the usual dosage.

Side Effects:

• Fatigue
• Headache
• Nausea
• Vomiting
• Fever
• Cough
• Insomnia
• Liver Function Abnormalities
• Allergic Reactions

Safety Advise:

Kidney  

Monitor kidney function regularly, as Tafnat can cause nephrotoxicity. Kindly speak with your healthcare provider.

Liver  

Monitor liver function regularly, as Tafnat can cause liver impairement. Kindly speak with your healthcare provider.

Pregnancy  

Tafnat should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Tafnat while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Alcohol  

Tafnat should not be taken with alcohol. Kindly speak with your healthcare provider.

Storage:

Store Tafnat Tablet at a temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in the original packaging to protect them from light and moisture. Keep out of reach of children.

How to use this Medication?

Drink a glass of water along with this prescription. Take it daily at the same time as specified on the prescription label. Consume it with food. Take each dose exactly as directed on the prescription label for the best potential outcome from your therapy. Don't miss any dosages. The virus may become resistant to this and other medications if doses are skipped. Unless instructed otherwise by your care team, continue taking this therapy. 

Discuss the usage of this drug in children with your care team. For certain illnesses, it can be administered to youngsters as young as 12, although there are safety precautions to take.

References:

1.   De Clercq E. Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF). Biochemical pharmacology. 2016 Nov 1;119:1-7.

2.  Wassner C, Bradley N, Lee Y. A review and clinical understanding of tenofovir: tenofovir disoproxil fumarate versus tenofovir alafenamide. Journal of the International Association of Providers of AIDS Care (JIAPAC). 2020 Apr 15;19:2325958220919231.

3.   Scott LJ, Chan HL. Tenofovir alafenamide: a review in chronic hepatitis B. Drugs. 2017 Jun;77(9):1017-28.

4.  Gibson AK, Shah BM, Nambiar PH, Schafer JJ. Tenofovir alafenamide: a review of its use in the treatment of HIV-1 infection. Annals of Pharmacotherapy. 2016 Nov;50(11):942-52.

Disclaimer:

The main goal of Apothecare is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place. 

Marketer details

Name: Natco Pharma Ltd

Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India

Frequently Asked Questions (FAQs):

1. What is a Tafnat 25mg Tablet?

Tafnat 25mg contains Tenofovir Alafenamide, an antiviral medication. It may be prescribed for the treatment of chronic hepatitis B virus (HBV) infection. Strict adherence to a hepatologist's oversight is required.

2. How may Tafnat work?

It is believed to inhibit the reverse transcriptase enzyme, which may potentially suppress the replication of the hepatitis B virus and reduce liver inflammation.

3. What conditions may it be prescribed for?

It is considered for adults and adolescents with chronic hepatitis B infection, based on viral load testing ordered by a doctor.

4. How is it administered?

It is typically taken orally once daily. Adhering strictly to a consistent daily schedule is crucial for optimal potential efficacy.

5. Can it be taken with food?

Yes, it is generally advised to take it with food. You must adhere to the specific dietary intake advice provided by your healthcare provider.

6. What are the possible side effects?

Patients may potentially experience headache, nausea, fatigue, or abdominal pain. Discuss any ongoing side effects with your physician.

7. Does it cure Hepatitis B?

It is not a cure; it may potentially help suppress the virus. Long-term adherence to the medication is typically required to maintain viral suppression.

8. Are there bone or kidney risks?

While designed to have potentially less impact on bones and kidneys, adherence to regular safety monitoring by your doctor remains essential.

9. Can I stop taking it abruptly?

Stopping the medication without a doctor's approval may potentially lead to a severe flare-up of hepatitis. Adhere strictly to your doctor's protocols if stopping is required.

10. Does it prevent transmission?

It does not prevent the potential transmission of HBV to others. Adherence to safe practices is required to protect others.

11. Can it be used in pregnancy?

It may be considered during pregnancy if clinically necessary. You must strictly adhere to an obstetrician's guidance to manage potential risks.

12. Is Tafnat a prescription medicine?

Yes, it is a prescription-only antiviral medication.

Medical Disclaimer:

Tafnat 25mg Tablet is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.