Pazeqol 400mg Tablet contains Pazopanib, is a protein kinase inhibitor used to treat soft tissue sarcoma and kidney cancer.

Brand Name: Pazeqol

Composition: Pazopanib

Mechanism of Action:

Pazopanib inhibits multiple kinases, Vascular endothelial growth factor receptors, Platelet-derived growth factor receptors and Fibroblast growth factor receptors. By blocking these pathways, pazopanib reduces tumor growth and inhibits the development of new blood vessels that tumors need to grow.

Uses:

·         Renal Cell Carcinoma

·         Soft Tissue Sarcoma

Side effects:

·         Hypertension (high blood pressure)

·         Diarrhea

·         Nausea

·         Vomiting

·         Dizziness

·         Fatigue

·         Liver function abnormalities

·         Skin rash

·         Sever liver damage

Dosage and Administration:

Oral tablets of Pazopanib are typically taken once day. To optimize absorption, it is advised to take it empty-handed, either an hour before or two hours after meals. The usual starting dose for pazopanib is 400 mg once day, however this might change depending on the ailment being treated.

Safety Advise: 

Lungs  

The safety of Pazeqol for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Pazeqol for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Pazeqol for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Pazeqol should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Pazeqol while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Storage in 30 °C, keep away from children and place out of sun light.

How to take this medication?

Take this medication orally while drinking a glass of water. Observe the medicine label's instructions. This medication should not be sliced, crushed, or chewed. At least one hour before or two hours after meals, take this medication on an empty stomach. Avoid taking it with meals.

Avoid taking grapefruit juice with it. Take your medication on a regular basis. Avoid taking it more frequently than prescribed. Except as directed by your physician, do not discontinue taking.

Contact an emergency department or poison control center right away if you believe you have taken too much of this medication.

References:

1.     Bukowski RM, Yasothan U, Kirkpatrick P. Pazopanib. Nature reviews Drug discovery. 2010 Jan;9(1):17-8.

2.     Sonpavde G, Hutson TE. Pazopanib: a novel multitargeted tyrosine kinase inhibitor. Current oncology reports. 2007 Jan;9:115-9.

3.     Miyamoto S, Kakutani S, Sato Y, Hanashi A, Kinoshita Y, Ishikawa A. Drug review: pazopanib. Japanese Journal of Clinical Oncology. 2018 Jun;48(6):503-13.

4.     Pick AM, Nystrom KK. Pazopanib for the treatment of metastatic renal cell carcinoma. Clinical therapeutics. 2012 Mar 1;34(3):511-20.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India