Lentykine 4mg Capsule

Lentykine 4 mg Capsules contains Lenvatinib. An oral multi-kinase inhibitor called lentinib is mainly used to treat different kinds of cancer.

Brand Name: Lentykine

Composition: Lenvatinib

Mechanism of Action:

Lenvatinib functions by blocking a variety of receptor tyrosine kinases (RTKs), among them the VEGF receptors, which are implicated in angiogenesis—the process of forming new blood vessels—which fuels the growth of tumors. It slows the growth and spread of tumors by obstructing these routes.

Uses:

• Thyroid Cancer
• Endometrial Cancer
• Kidney Cancer
• Liver Cancer

Dosage and Administration:

The type of cancer and the patient's characteristics (weight, health) determine the dosage. The oncologist will prescribe a dose of 4 mg, 8 mg, or 12 mg once day. Orally administered either with or without food.

Side Effects:

• Hypertension
• Diarrhea
• Fatigue
• Nausea
• Vomiting
• Loss of appetite
• Weight loss
• Stomatitis
• Blood Clot
• Headache
• Fever
• Confusion
• Chest Pain

Safety Advise:

Kidney  

Patients with kidney illness should use Lentykine 4 Capsule with caution. Lentykine 4 Capsule dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Liver  

Patients with liver illness should use Lentykine 4 Capsule with caution. Lentykine 4 Capsule dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Pregnancy  

Since it may injure the fetus, Lentykine 4 mg Capsule should not be used while pregnant. It is advised not to use this medication when pregnant. Kindly speak with your healthcare provider.

Breast Feeding  

Lenvatinib may pass into breast milk. Talk to your healthcare provider about whether to stop taking the medication or to keep breastfeeding.

Alcohol  

When taking Lentykine 4mg Capsule, it is advisable to stay away from alcohol since it may raise your risk of experiencing some of the medication's negative effects. Kindly speak with your healthcare provider.

Storage:

Keep stored at room temperature, preferably between 20°C and 25°C (68°F and 77°F). Avoid careful of extremely cold or freezing conditions.

How to use this Medication?

Swallow the capsules whole, without crushing, chewing, or chopping them up. Take this medication orally along with a glass of water. Pay close attention to the directions on the prescription label, taking it as directed by your doctor and only stop when directed.

Consult your pediatrician about the usage of this medication in young patients. There might be a need for extra caution. 

Get in touch with an emergency department or poison control center right away if you believe you may have taken too much of this medication.

References:

1.      Al-Salama ZT, Syed YY, Scott LJ. Lenvatinib: a review in hepatocellular carcinoma. Drugs. 2019 Apr 1;79:665-74.

2.      Hao Z, Wang P. Lenvatinib in management of solid tumors. The oncologist. 2020 Feb 1;25(2):e302-10.

3.      Hatanaka T, Naganuma A, Kakizaki S. Lenvatinib for hepatocellular carcinoma: a literature review. Pharmaceuticals. 2021 Jan 6;14(1):36.

4.      Cabanillas ME, Habra MA. Lenvatinib: Role in thyroid cancer and other solid tumors. Cancer treatment reviews. 2016 Jan 1;42:47-55.

Disclaimer:

The main goal of Apothecare is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India 

Frequently Asked Questions (FAQs):

1. What is Lentykine 4mg Capsule?

Lentykine 4mg contains Lenvatinib, an oral targeted therapy (kinase inhibitor). It may be prescribed for the management of certain types of advanced cancers.

2. How may Lenvatinib work?

It is believed to inhibit multiple receptor tyrosine kinases involved in tumour blood vessel growth and cancer cell progression. This may potentially slow down tumour growth.

3. What conditions may it be prescribed for?

It may be considered for locally recurrent or metastatic thyroid cancer, advanced renal cell carcinoma, and unresectable hepatocellular carcinoma (liver cancer).

4. How is Lentykine 4mg taken?

It is taken orally once a day. It may generally be taken with or without food.

5. What is the usual dose?

The prescribed dose depends on the type of cancer being treated and may involve taking multiple 4mg or 10mg capsules at once, as strictly directed by your oncologist.

6. What are the possible side effects?

Patients may potentially experience high blood pressure, fatigue, diarrhoea, decreased appetite, weight loss, or voice hoarseness.

7. Are there serious cardiovascular risks?

Yes, it may potentially cause severe hypertension, cardiac dysfunction, or arterial thromboembolic events (like heart attack or stroke).

8. Does it require regular blood pressure monitoring?

Blood pressure is usually closely monitored before and during treatment, as it may frequently cause significant increases in blood pressure.

9. Can it cause liver or kidney problems?

It may potentially affect liver and kidney function, requiring routine blood tests to monitor these organs.

10. Is it safe during pregnancy?

Lenvatinib may cause fetal harm and is generally not recommended during pregnancy. Effective contraception may be required.

11. What if I vomit after taking a dose?

If vomiting occurs after taking a capsule, it is typically advised not to take an additional dose but to take the next scheduled dose the following day.

12. Is Lentykine a prescription medicine?

Yes, it is a prescription-only oncology medication.

Medical Disclaimer:

Lentykine 4mg Capsule is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.