Letall 2.5mg Tablet contains Letrozole, which is an aromatase inhibitor primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. The growth of certain breast cancers depends on the synthesis of estrogen, which letrozole inhibits.

Brand Name: Letall

Composition: Letrozole

Mechanism of Action:

Inhibiting the aromatase enzyme, which changes androgens into estrogen, is how letrozole functions. Letrozole slows or stops the growth of estrogen-sensitive breast cancers by reducing estrogen levels.

Uses:

Breast Cancer

Dosage and Administration:

2.5mg every day. suitable for both food and non-food consumption. Consistent use at the same time every day is recommended.

Side Effects:

·         Rash

·         Hypertension

·         Diarrhea

·         Fatigue

·         Nausea

·         Vomiting

·         Shortness of breath

·         Bone pain

·         Anemia

·         Loss of appetite

·         Sweating

·         Bone thinning

·         Cough

Safety Advise:

Liver  

Letrozole can harm the liver and raise liver enzymes. Regular liver function tests are recommended, particularly for people who already have liver disease. Kindly speak with your healthcare provider.

Kidney    

Regular kidney function tests are recommended, particularly for people who already have renal disease. Kindly speak with your healthcare provider.

Pregnancy  

Letrozole may be harmful to the developing fetus. During treatment, effective contraception should be used. Kindly speak with your healthcare provider.

Breast Feeding  

It is not known if Letrozole is excreted in breast milk; therefore, breastfeeding is generally not recommended during treatment. Kindly speak with your healthcare provider.

Alcohol  

The safety of combining Letall 2.5mg Tablet with alcohol is unknown. Kindly speak with your healthcare provider.

Storage:

Store at room temperature (15°C to 30°C) in a dry place, away from light and moisture.

How to use this Medication?

Drink a glass of water along with this prescription. When taking it, you can eat or not. Observe the medicine label's instructions. Take your prescription drug on a regular basis. Never take your prescription more frequently than is recommended. Except as directed by your care team, do not stop taking.

Discuss the usage of this drug in children with your care team. Extra caution could be required.

References:

1.    Haynes BP, Dowsett M, Miller WR, Dixon JM, Bhatnagar AS. The pharmacology of letrozole. The Journal of steroid biochemistry and molecular biology. 2003 Oct 1;87(1):35-45.

2.      Bhatnagar AS. The discovery and mechanism of action of letrozole. Breast cancer research and treatment. 2007 Oct;105(Suppl 1):7-17.

3.      Simpson D, Curran MP, Perry CM. Letrozole: a review of its use in postmenopausal women with breast cancer. Drugs. 2004 Jun;64:1213-30.

4.    Mukherjee AG, Wanjari UR, Nagarajan D, Vibhaa KK, Anagha V, Chakraborty R, Renu K, Dey A, Vellingiri B, Gopalakrishnan AV. Letrozole: Pharmacology, toxicity and potential therapeutic effects. Life sciences. 2022 Dec 1;310:121074.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India