Cefactiv 2.5gm Injection

Cefactiv 2.5gm Injection contains Ceftazidime, Avibactam, is an antibiotic injection is used to treat serious bacterial infections of the stomach, urinary system and lungs. It can be used to treat a variety of illnesses in both adults and children, either by itself or in combination with other antibiotics like metronidazole. 

Brand Name: Cefactiv

Composition: Ceftazidime, Avibactam

Mechanism of Action:

Ceftazidime is a third-generation cephalosporin antibiotic that causes cell lysis and death by preventing the formation of bacterial cell walls. Avibactam is an non-beta-lactam beta-lactamase inhibitor that increases ceftazidime's effectiveness against infections that manufacture beta-lactamases by shielding it from being broken down by specific enzymes made by resistant bacteria.

Uses:

·         Urinary tract infections

·         Intra-abdominal infections

·         Hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia.

Side effects: 

·       Fatigue

·       Hot flashes

·       Hypertension

·       Nausea

·       Vomiting

·       Allergic reactions (anaphylaxis)

·       Renal impairment

·       Seizures

Dosage and Administration:

Administered through intravenously, typically over a period of 2 hours. Dosage and duration depend on the type and severity of the infection, as well as patient factors such as renal function

Safety Advise:

Kidney  

Cefactiv 2.5gm injection is safe to take in renal disease patients. Cefactiv 2.5gm injection should be taken exactly as prescribed.

Pregnancy  

Cefactiv 2.5gm injection is extremely dangerous to consume when pregnant. Seek counsel from your doctor, as research on pregnant women and animals have indicated considerable risk to the growing infant.

Breast Feeding

Cefactiv 2.5gm injection is not safe to take when breast feeding. Data reveal that the medicine may be hazardous to the infant. 

Storage:

Keep out of direct sunlight and in a cool, dry location. As stated in the product literature, adhere to the particular storage instructions after reconstitution.

How to use this medicine?

Every 8 to 12 hours, this drug is injected into a vein or muscle; the dosage for children is determined by their weight and medical condition. Before using, check for particles or discoloration, and ask your healthcare provider how to properly prepare and store it. Before using a pre-mixed solution that has been frozen, defrost it at room temperature or in the refrigerator and give it a good shake. To get the most out of the antibiotic, give it at equally spaced intervals.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India

Frequently Asked Questions:

1. What is Cefactiv 2.5gm Injection?
Cefactiv 2.5gm is a combination antibiotic injection containing Cefoperazone (2g) and Sulbactam (1g). It may be prescribed for serious bacterial infections caused by susceptible organisms, particularly in hospital settings.

2. How does Cefactiv work?
Cefoperazone is a third-generation cephalosporin antibiotic that may inhibit bacterial cell wall synthesis, potentially leading to bacterial death in susceptible organisms. Sulbactam is a beta-lactamase inhibitor that may protect Cefoperazone from certain bacterial resistance enzymes, potentially broadening its antibacterial coverage.

3. What types of infections may Cefactiv be used for?
Cefactiv may be considered for the treatment of infections such as:
•         Hospital-acquired pneumonia
•         Urinary tract infections
•         Intra-abdominal infections (e.g., peritonitis, biliary tract infections)
•         Gynaecological infections
•         Skin and soft tissue infections
•         Bacteraemia (bloodstream infections)
Effectiveness depends on the susceptibility of the causative organism, as determined by culture and sensitivity testing.

4. How is Cefactiv 2.5gm administered?
It is administered as an intravenous (IV) infusion or intramuscular (IM) injection by a healthcare professional in a hospital or clinical setting.

5. What is the usual dosage of Cefactiv?
The typical adult dose is 2.5g every 12 hours, which may be increased to every 8 hours for more severe infections. Dosage adjustments may be required in patients with hepatic or renal impairment. Follow your doctor's prescribed regimen.

6. What are the possible side effects of Cefactiv?
Some patients may experience:
•         Diarrhoea (including, rarely, Clostridioides difficile-associated colitis)
•         Skin rash
•         Elevated liver enzymes
•         Injection site reactions
•         Nausea or vomiting
Inform your doctor promptly if any side effects are severe or unexpected.

7. Is Cefactiv safe for patients with a penicillin allergy?
There is a possibility of cross-reactivity between penicillins and cephalosporins, though this risk is considered low. If you have a known penicillin allergy, it is essential to inform your doctor before receiving Cefactiv so that an appropriate risk assessment can be made.

8. Does Cefactiv interact with alcohol?
Cefoperazone may cause a disulfiram-like reaction in some patients when alcohol is consumed, which can include flushing, nausea, vomiting, and rapid heartbeat. Alcohol should be avoided during the course of treatment and for several days after the final dose.

9. Can Cefactiv be used during pregnancy?
Use during pregnancy should be considered only when the clinical benefit clearly outweighs the potential risk, as determined by a physician. Consult your doctor regarding safety during pregnancy or breastfeeding before receiving this injection.

10. Is Cefactiv a prescription-only medicine?
Yes. Cefactiv 2.5gm is a prescription-only injectable antibiotic administered exclusively in a hospital or clinical setting under physician supervision.

Medical Disclaimer:
Cefactiv 2.5gm Injection is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.