Aprecap 150mg Injection contains Fosaprepitant, which is a prodrug of aprepitant. It is an antiemetic drug used to stop nausea and vomiting that come with surgery and chemotherapy.

Brand Name: Aprecap

Composition: Fosaprepitant

Mechanism of Action:

The body quickly transforms Fosaprepitant into Aprepitant after it is administered. Aprepitant blocks the function of substance P, a neurotransmitter involved in the vomiting reflex, by acting as an antagonist of the neurokinin-1 (NK1) receptor. This successfully prevents nausea and vomiting, both acute and delayed.

Uses:

Prevention of Nausea and Vomiting due to Chemotherapy

Dosage and Administration:

An intravenous dose of 150 mg fosaprepitant is typically given 30 minutes prior to the initiation of chemotherapy.

Side Effects:

• Fatigue
• Dizziness
• Headache
• Diarrhea
• Hiccup
• Constipation

Safety Advise:

Liver  

Caution is advised in patients with hepatic impairment, and dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Kidney  

Caution is advised in patients with renal impairment, and dosage adjustments may be necessary. Kindly speak with your healthcare provider.

Pregnancy  

It should only be used if absolutely necessary because its safety during pregnancy has not been thoroughly demonstrated. Kindly speak with your healthcare provider.

Breast Feeding  

Using Aprecap 150mg Injection while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Alcohol  

Alcohol consumption while using Aprecap 150mg Injection is not advised. Kindly speak with your healthcare provider.

Storage:

Aprecap Injection should be kept out of direct sunlight and at room temperature, between 20°C and 25°C.

How to use this Medication?

Whereas fosaprepitant injection is a powder prepared for intravenous usage and usually given as a single dosage prior to chemotherapy on day 1, aprepitant injection is an emulsion. On days two and three of the treatment cycle, oral aprepitant may be administered for adults undergoing certain chemotherapy regimens as well as children and adolescents receiving aprepitant.

If you have a rash, dizziness, trouble breathing, a fast heartbeat, or swelling around your eyes during or soon after having an injection of aprepitant or fosaprepitant, notify your doctor right away so they can stop the infusion and treat the response.

Disclaimer:

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