Plamumab 40mg Injection contains Adalimumab, which is a monoclonal antibody that targets and inhibits tumor necrosis factor-alpha (TNF-α), a cytokine involved in systemic inflammation.

Brand Name: Plamumab

Composition: Adalimumab

Mechanism of Action:

Adalimumab reduces inflammation and immune system activity by binding to TNF-α and blocking its interaction with cell surface receptors. This activity aids in reducing the symptoms of a number of inflammatory diseases.

Uses:

• Rheumatoid Arthritis
• Psoriatic Arthritis
• Ankylosing Spondylitis
• Crohn's Disease
• Ulcerative Colitis

Dosage and Administration:

The disease being treated and the patient's reaction determine the amount and frequency of administration. Usually, it can be injected subcutaneously, with maintenance doses given at predetermined intervals after the initial dose.

Side Effects:

·       Nausea

·       Vomiting

·       Diarrhea

·       Dizziness

·       Fever

·       Rash

·       Headache

·       Allergic reactions

·       Seizures

·       Thrombocytosis

Safety Advise:

Kidney  

Dose adjustments are required in patients with renal impairment. Kindly speak with your healthcare provider.

Liver  

Liver function tests should be monitored during prolonged treatment, especially in patients with liver disease. Kindly speak with your healthcare provider.

Pregnancy  

Use Plamumab during pregnancy only if clearly needed and under medical supervision, as its safety during pregnancy is not fully established.  Kindly speak with your healthcare provider.

Breast Feeding  

Caution is advised during breastfeeding since the drug can pass into breast milk. Kindly speak with your healthcare provider.

Driving    

Your ability to drive may be impacted by adverse effects from Plamumab Injection. Kindly speak with your healthcare provider.

Storage:

Store Plamumab Injection in the refrigerator (2-8°C) and protect it from light. It should not be frozen.

How to use this medication?

Adalimumab is available in various forms, including prefilled syringes and vials for subcutaneous injection, with dosing guided by your doctor based on your condition and age. Follow your prescription instructions carefully, mark your injection schedule on a calendar, and consult your doctor or pharmacist if you have any questions.

You will receive your first dose of adalimumab injection products in your doctor's office. Following that, you can administer adalimumab injections yourself or have a friend or family member do it for you. Read the printed instructions included with adalimumab injection products before using them for the first time. Ask your physician or pharmacist to demonstrate how to inject the drug for you or the person administering it.

References:

1.      Scheinfeld N. Adalimumab: a review of side effects. Expert opinion on drug safety. 2005 Jul 1;4(4):637-41.

2.      Mease PJ. Adalimumab in the treatment of arthritis. Therapeutics and clinical risk management. 2007 Mar 30;3(1):133-48.

3.      Lapadula G, Marchesoni A, Armuzzi A, Blandizzi C, Caporali R, Chimenti S, Cimaz R, Cimino L, Gionchetti P, Girolomoni G, Lionetti P. Adalimumab in the treatment of immune-mediated diseases. International Journal of Immunopathology and Pharmacology. 2014 Jan;27(1_suppl):33-48.

4.      Ellis CR, Azmat CE. Adalimumab.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India