Crizalk 250mg Capsule contains Crizotinib, a tyrosine kinase inhibitor that targets ALK (anaplastic lymphoma kinase) and ROS1 gene rearrangements. Patients with advanced non-small cell lung cancer that is ROS1-positive or ALK-positive are treated with it.

Brand Name: Crizalk

Composition: Crizotinib

Mechanism of Action:

Tyrosine kinase inhibitors (TKIs), such as crizotinib, target ROS1 and ALK (anaplastic lymphoma kinase), which are both aberrantly active in some malignancies and promote unchecked cell growth. Crisotinib stops the growth of cancer cells and encourages their death by blocking ALK and ROS1, two important signaling pathways.

Uses:

Non-small cell lung cancer

Dosage and Administration:

Take 250 mg twice daily, either with or without food. Completely swallow the capsule. Avoid chewing, crushing, or opening the capsule.

Side Effects:

·       Blurred vision

·       Floaters

·        Nausea

·       Vomiting

·       Diarrhea

·       Constipation

·       Fatigue

·       Double vision

·       Edema (swelling)

·       Decreased appetite

Safety Advise:

Liver  

Periodic liver function tests should be performed as the drug may increase liver enzymes, indicating liver stress or damage. Kindly speak with your healthcare provider.

Kidney  

Patients with moderate kidney impairment may require dosage adjustments. Crizotinib is not recommended in cases of severe renal impairment. Kindly speak with your healthcare provider.

Pregnancy  

The use of Crizotinib during pregnancy is not recommended unless clearly necessary due to a lack of sufficient data on its safety. Kindly speak with your healthcare provider.

Breastfeeding  

It is unknown whether Crizotinib is excreted in human milk, so caution should be exercised if a mother is breastfeeding. Kindly speak with your healthcare provider.

Alcohol  

Your ability to drive may typically be impacted by Crizalk 250mg Capsule. Kindly speak with your healthcare provider.

Storage:

Store at room temperature (20-25°C or 68-77°F). Keep the medication in a dry place, away from excessive moisture and light.

How to use this medication?

This medication should be taken orally with water. Take it daily at the same time as specified on the prescription label. This medication should not be sliced, crushed, or chewed. Completely swallow the capsules. It can be taken with or without meals. Take it with meals if it makes you feel nauseous. Unless instructed otherwise by your healthcare provider, continue taking it.

Avoid taking grapefruit juice with this medication.

With every prescription and refill, the pharmacist will provide you with a unique MedGuide. Every time, make sure to carefully read this information.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Pfizer Ltd

Address: The Capital, 1802, 18th Floor, Plot No. C-70, ‘G’ Block, Bandra Kurla Complex, Bandra East, Mumbai – 400051.

Country of origin: India