Terifrac 750mcg Injection

Terifrac 750mcg Injection contains Teriparatide, a synthetic version of human parathyroid hormone (PTH). By encouraging the growth of new bone, it is used to treat specific bone disorders.

Brand Name: Terifrac

Composition: Teriparatide

Mechanism of Action:

A recombinant version of parathyroid hormone called teriparatide aids in controlling the metabolism of phosphorus and calcium in bones. It increases bone density and fosters the growth of new bone by stimulating osteoblasts, the cells that make up bone.

Uses:

·         Osteoporosis in Postmenopausal Women

·         Primary or Hypogonadal Osteoporosis in Men

·         Glucocorticoid-Induced Osteoporosis

Dosage and Administration:

Typically, 20mcg once daily is administered as a subcutaneous injection, usually into the thigh or abdomen.

Side Effects:

• Nausea
• Dizziness
• Pain at the injection site
• Hypercalcemia
• Joint pain

Safety Advise: 

Kidney  

Patients with renal impairment may need dose adjustments. Kindly speak with your Healthcare provider.

Liver  

Information about the use of Terifrac Injection in liver disease patients is limited. Kindly speak with your Healthcare provider.

Pregnancy  

Use of Terifrac is generally not recommended during pregnancy. Kindly speak with your Healthcare provider.

Breast Feeding  

Use of Terifrac is generally not recommended during breastfeeding. Kindly speak with your Healthcare provider.

Alcohol  

When taking alcohol with Terifrac Injection, caution is advised. Kindly speak with your Healthcare provider.

How to use this Medication?

This medication is injected subcutaneously. You will learn how to administer and prepare this medication. Use precisely as instructed. Take your medication on a regular basis. Never take your medication more frequently than prescribed.

Your pharmacist will provide you with a unique MedGuide with every prescription and refill. Every time, make sure to carefully read this information.

Consult your pediatrician about the usage of this medication in young patients. There might be a need for extra caution.

References:

1.      Quattrocchi E, Kourlas H. Teriparatide: a review. Clinical therapeutics. 2004 Jun 1;26(6):841-54.

2.      Lindsay R, Krege JH, Marin F, Jin L, Stepan JJ. Teriparatide for osteoporosis: importance of the full course. Osteoporosis international. 2016 Aug;27:2395-410.

3.      Blick SK, Dhillon S, Keam SJ. Teriparatide: a review of its use in osteoporosis. Drugs. 2008 Dec;68:2709-37.

4.     Saag KG, Shane E, Boonen S, Marín F, Donley DW, Taylor KA, Dalsky GP, Marcus R. Teriparatide or alendronate in glucocorticoid-induced osteoporosis. New England Journal of Medicine. 2007 Nov 15;357(20):2028-39.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

Frequently Asked Questions:

1. What is Terifrac 750mcg Injection?
Terifrac 750mcg Injection contains Teriparatide, a recombinant form of human Parathyroid Hormone (PTH 1–34). It may be prescribed for the treatment of severe osteoporosis and to help reduce the risk of fractures in patients who are at significant risk. Individual suitability must be assessed by a specialist.

2. How does Teriparatide in Terifrac work?
Unlike anti-resorptive treatments such as bisphosphonates, Teriparatide is an anabolic agent that is believed to stimulate the formation of new bone by activating osteoblasts. This may lead to improvements in bone density and bone structure in some patients, though outcomes can vary.

3. Who may be considered for Terifrac?
Terifrac may be prescribed for:
•         Postmenopausal women with severe osteoporosis at high fracture risk
•         Men with primary or hypogonadal osteoporosis at significant fracture risk
•         Patients with glucocorticoid-induced osteoporosis who are at high risk of fractures
Eligibility is assessed by your specialist based on bone density and fracture risk.

4. How is Terifrac administered?
Terifrac is administered as a daily subcutaneous injection (20mcg per day) into the abdomen or thigh. Patients may be trained to self-administer the injection at home after receiving appropriate guidance from a healthcare professional.

5. What are the possible side effects of Terifrac?
Some patients may experience:
•         Nausea
•         Leg cramps
•         Dizziness
•         Headache
•         Orthostatic hypotension (dizziness upon standing) in some patients
Not all patients will experience these effects. Consult your doctor if any side effects are persistent or concerning.

6. Are there patients for whom Terifrac may not be suitable?
Terifrac may not be appropriate for:
•         Patients with a history of bone cancer or metastatic bone disease
•         Patients with unexplained elevation of bone alkaline phosphatase
•         Those with pre-existing hypercalcaemia
•         Children and young adults with open growth plates (epiphyses)
Your specialist will review your complete medical history before prescribing.

7. How long should Terifrac be used?
Teriparatide treatment is generally limited to a maximum of 24 months over a patient's lifetime. After completing the course, your doctor may recommend transitioning to an anti-resorptive therapy to help maintain bone density gains that may have been achieved.

8. May Terifrac require calcium and vitamin D supplementation?
Adequate calcium and vitamin D intake is generally recommended during Teriparatide treatment to support bone mineralisation and reduce the risk of hypocalcaemia. Your doctor will advise on appropriate supplementation.

9. How should Terifrac be stored?
Store in a refrigerator (2°C–8°C). Do not freeze. Once opened, the pen should be kept refrigerated and discarded after 28 days or as specified in the product instructions.

10. Is Terifrac a prescription-only injection?
Yes. Terifrac is a prescription-only osteoporosis treatment available exclusively under the supervision of an endocrinologist, rheumatologist, or orthopaedic specialist.

Medical Disclaimer:
Terifrac 750mcg Injection is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.