Eltromag 50mg Tablet

Eltromag 50mg Tablet contains Eltrombopag, is used to treat low platelet counts brought on by chronic hepatitis C virus infection or chronic immunological (idiopathic) thrombocytopenic purpura. Additionally, severe aplastic anemia is treated with it. 

Brand Name: Eltromag

Composition: Eltrombopag

Mechanism of Action:

Eltrombopag's mechanism of action is similar to that of thrombopoietin, a natural hormone that stimulates the production of platelets from megakaryocytes in the bone marrow. Eltrombopag increases platelet production by promoting the proliferation and differentiation of megakaryocyte progenitors through the activation of the thrombopoietin receptor.

Uses:

·         Chronic immune thrombocytopenia

·         Thrombocytopenia in Chronic Hepatitis C Patients

·         Aplastic Anemia

Side effects:

·         Nausea

·         Vomiting

·         Fatigue

·         Headache

·         Diarrhea

·         Dizziness

·         Thrombotic events (blood clots)

·         Hepatotoxicity (liver damage)

·         Bone marrow fibrosis

Dosage and Administration:

Eltromag is administered as orally. Depending on the ailment being treated, different amounts are advised; typical dosages range from 25 mg to 75 mg once day, with adjustments made based on response and platelet counts. It should be taken regularly in relation to meals, whether it is taken with or without food.

Safety Advise:

Lungs  

The safety of Eltromag for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Eltromag for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Eltromag for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Eltromag should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Eltromag while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:        

Storage in 30 °C, keep away from children and place away from sun light.

How to use this Medication?

Take this medication orally. Take this medication with a low-calcium meal, on an empty stomach, or at least 30 minutes before or two hours after eating. For two hours before and four hours after taking this medication, stay away from foods high in calcium, antacids, aluminum, calcium, iron, magnesium, selenium, and zinc products. Take your medication on a regular basis. Avoid taking it more frequently than prescribed. Except as directed by your physician, do not discontinue taking.

Contact an emergency department or poison control center right away if you believe you have taken too much of this medication.

References:

1.      Garnock-Jones KP, Keam SJ. Eltrombopag. Drugs. 2009 Mar;69:567-76.

2.    Bussel JB, Cheng G, Saleh MN, Psaila B, Kovaleva L, Meddeb B, Kloczko J, Hassani H, Mayer B, Stone NL, Arning M. Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura. New England Journal of Medicine. 2007 Nov 29;357(22):2237-47.

3.      Scheinberg P. Activity of eltrombopag in severe aplastic anemia. Blood Advances. 2018 Nov 13;2(21):3054-62.

4.      Bussel JB, Pinheiro MP. Eltrombopag. Hematopoietic Growth Factors in Oncology. 2010 Oct 18:289-303.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India

Frequently Asked Questions:

1. What is Eltromag 50mg Tablet?
Eltromag 50mg contains Eltrombopag, a thrombopoietin receptor agonist. It may be prescribed for the management of chronic immune thrombocytopenia (ITP) – a condition associated with low platelet counts – and for severe aplastic anaemia in certain patients. Individual suitability must be assessed by a haematologist.

2. How does Eltrombopag work?
Eltrombopag is believed to stimulate thrombopoietin receptors on bone marrow stem cells, which may promote the production and maturation of platelets. This may help increase platelet counts in some patients, though responses can vary considerably.

3. What conditions may Eltromag be prescribed for?
Eltromag may be considered for:
•         Chronic immune thrombocytopenia (ITP) in adults and children aged 1 year and older
•         Severe aplastic anaemia (in combination with immunosuppressive therapy, in some patients)
•         Thrombocytopenia in certain patients with chronic hepatitis C undergoing interferon-based therapy
Eligibility is determined by your haematologist after a thorough clinical evaluation.

4. How is Eltromag 50mg taken?
It is taken orally once daily, generally on an empty stomach or at least 2 hours before or 4 hours after food, antacids, or dairy products, to allow adequate absorption. Follow your doctor's instructions on the timing carefully.

5. What is the usual dose of Eltromag?
The starting dose is typically 25–50mg once daily, adjusted based on platelet response and tolerability. The maximum dose is generally 75mg per day, though your doctor may prescribe differently based on your clinical picture.

6. What are the possible side effects of Eltromag?
Some patients may experience:
•         Nausea
•         Diarrhoea
•         Headache
•         Elevated liver enzymes (hepatotoxicity – which may require monitoring)
•         Cataract formation with long-term use
•         Anaemia
Not all patients will experience these effects. Inform your doctor if you notice any new or worsening symptoms.

7. Are there serious risks associated with Eltromag?
Some patients may be at risk of more serious adverse events, including:
•         Hepatotoxicity (liver injury) – liver function must be regularly monitored
•         Thrombotic or thromboembolic events (blood clot formation) in some patients
•         Bone marrow fibrosis with prolonged use in some cases
Your doctor will monitor for these risks during treatment.

8. Are there any dietary restrictions while taking Eltromag?
Yes. Certain foods and supplements – including dairy products, calcium-rich foods, antacids, and mineral supplements – may significantly reduce the absorption of Eltrombopag if consumed within 4 hours of taking the tablet. Please follow your doctor's or pharmacist's guidance on timing.

9. How often should liver function be monitored?
Liver function tests (LFTs) are generally recommended before starting treatment, every 2 weeks during dose adjustments, and monthly once the dose is stable. Your doctor will advise on the specific monitoring schedule for your situation.

10. Is Eltromag 50mg a prescription-only medicine?
Yes. Eltromag is a prescription-only medicine used under the supervision of a haematologist or specialist physician.

Medical Disclaimer:
Eltromag 50mg Tablet is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.