Imat 400mg Tablet contains Imatinib Mesylate is an oral medication primarily used in the treatment of specific cancers, particularly those associated with abnormal cell signaling pathways.

Brand Name: Imat

Composition: Imatinib mesylate

Mechanism of Action:

Selective tyrosine kinases, such as c-KIT and BCR-ABL (the fusion protein generated in CML) are inhibited by imatinib mesylate. Imatinib inhibits these kinases, which interferes with the signaling pathways that cause cell division and growth, reducing or preventing the formation of cancerous cells.

Uses:

Chronic Myeloid Leukemia

Gastrointestinal Stromal Tumors

Other hematological malignancies 

Dosage and Administration:

Usually taken once a day, either with or without meals. Depending on the particular condition and each person's reaction, the dosage may change. Take the capsule whole and swallow it. Avoid chewing or crushing.

Side Effects:

·         Nausea

·         Vomiting

·         Diarrhea

·         Fatigue

·         Edema

·         Skin rash

·         Muscle cramps

·         Liver dysfunction

·         Heart problems (such as fluid retention)

·         Severe allergic reactions: Such as swelling of the face, throat, or difficulty breathing

Safety Advise:

Allergy  

 If you have ever experienced allergies to imatinib or related drugs, Kindly speak with your healthcare provider.

  Liver  

 Patients with serious liver condition should use Imat 400mg tablet with caution. Kindly speak with your healthcare provider.

Kidney  

 Patients with serious renal condition should use Imat 400mg tablet with caution. Kindly speak with your healthcare provider.

Pregnancy  

Imatinib can impact fetal development, thus expectant mothers should talk to their healthcare professional about potential risks.

Breast Feeding  

 Imatinib can impact fetal development, women who are nursing should talk to their healthcare professional about any possible risk factors.

Alcohol  

 It's uncertain if drinking alcohol while taking Imat 400mg tablet is safe. Kindly speak with your healthcare provider.

Storage:

Keep in storage between 20 and 25°C (68 and 77°F). Keep clear of humidity and bright light. Keep children away from it.

How to use this Medication?

To avoid an upset stomach, take this medication orally along with a full glass of water and meals. Avoid free of grapefruit juice, adhere to the prescription's instructions, and stop only when directed by your physician.

Report any problems you are having swallowing the tablets to your physician, pharmacist, or other healthcare provider. They can offer you guidance. 

Consult your pediatrician about the usage of this medication in young patients. Precautions do apply even though this medication may be administered for some diseases in children as young as one year old.

References:

1.    Chabner BA, Barnes J, Neal J, Olson E, Mujagic H, Sequist L, Wilson W, Longo D, Mitsiades C, Richardson P. Targeted therapies: tyrosine kinase inhibitors, monoclonal antibodies, and cytokines. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 12th Ed. New York: Mc Graw Hill. 2011.

2.  Gharibo M, Patrick-Miller L, Zheng L, Guensch L, Juvidian P, Poplin E. A phase II trial of imatinib mesylate in patients with metastatic pancreatic cancer. Pancreas. 2008 May 1;36(4):341-5.

3.    Waller CF. Imatinib mesylate. Small Molecules in Oncology. 2009 Oct 7:3-20.

4.    Guilhot F. Indications for imatinib mesylate therapy and clinical management. The oncologist. 2004 Jun 1;9(3):271-81.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer Details:

Name: Zydus Healthcare Limited

Address: Zydus Tower, CTS No- 460/6 of Village Pahadi, Off I. B. Patel Road, Goregaon (East), Mumbai-400 063

Country of origin: India