Clexane 60mg Injection contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) that is used as an anticoagulant to prevent and treat blood clots. It is frequently used in a variety of illnesses that call for blood thinning and can lower the risk of pulmonary embolism (PE) and deep vein thrombosis (DVT).

Brand Name: Clexane

Composition: Enoxaparin Sodium

Mechanism of Action:

Blood clots are prevented by enoxaparin-induced enhancement of antithrombin III's activity, which inhibits Factor Xa and Factor IIa (thrombin). Compared to thrombin, Factor Xa is more impacted by it.

Uses:

• Deep Vein Thrombosis
• Pulmonary Embolism.
• Blood Clot Prevention in Dialysis

Dosage and Administration:

Enoxaparin is injected subcutaneously, usually in the abdomen; the dosage is determined by the indication. Once injection is complete, avoid rubbing the injection site.

Side Effects:

• Bleeding
• Injection site reactions (bruising, pain, redness)
• Thrombocytopenia
• Elevated liver enzymes
• Spinal/epidural hematomas
• Headache
• Fever
• Diarrhea

Safety Advise:

Kidney

Patients with kidney illness should use clexane injection with caution. Clexane injection dosage adjustments can be required. Kindly speak with your healthcare provider.

Liver

The use of clexane injection in individuals with liver dysfunction is not well-documented. Kindly speak with your healthcare provider.

  Pregnancy

Prior to beginning the 60 mg injection of clexane medication, let your healthcare provider know if you are pregnant, suspect you are pregnant, or are planning to become pregnant. 

Breast Feeding

It is strongly recommended that you speak with your healthcare provider before using an injection of clexane 60 mg if you are nursing a baby.

Alcohol

It is unknown if drinking alcohol while using an injection of clexane is safe. Kindly speak with your healthcare provider.

Storage:

Store the injection at a temperature between 15°C to 25°C (room temperature). Protection: Keep the injection away from light and moisture.

How to use this medication?

Enoxaparin is injected subcutaneously (under the skin), typically twice a day for 10-14 days. Follow your doctor's instructions exactly, and do not adjust the dose or frequency on your own.

Use enoxaparin as prescribed even if you feel good. enoxaparin should not be stopped without first consulting your doctor.

References:

1.    Casele HL, Laifer SA, Woelkers DA, Venkataramanan R. Changes in the pharmacokinetics of the low-molecular-weight heparin enoxaparin sodium during pregnancy. American journal of obstetrics and gynecology. 1999 Nov 1;181(5):1113-7.

2.     Saltissi D, Morgan C, Westhuyzen J, Healy H. Comparison of low-molecular-weight heparin (enoxaparin sodium) and standard unfractionated heparin for haemodialysis anticoagulation. Nephrology Dialysis Transplantation. 1999 Nov 1;14(11):2698-703.

Disclaimer:

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Marketer details

Name: Sanofi India Ltd

Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Country of origin: France