Evermil 10mg Tablet includes Everolimus, a medication that belongs to the class of drugs known as mTOR inhibitors (mammalian target of rapamycin inhibitors). It is mostly used to treat cancer as well as other illnesses.

Brand Name: Evermil

Composition: Everolimus

Mechanism of Action:

The mTOR pathway, which is essential for cell division, growth, and survival, is inhibited by everolimus. Everolimus inhibits mTOR, which decreases cell division and limits the growth of cancerous cells.

Uses:

• Kidney Cancer (Advanced renal cell carcinoma)
• Neuroendocrine tumors of pancreatic origin
• Hormone receptor-positive breast cancer
• Tuberous Sclerosis Complex

Dosage and Administration:

The typical dosage is 10 mg once daily, but it can vary based on the specific condition being treated and the patient's response. Taken orally, with or without food. It is important to take it consistently at the same time each day.

Side Effects:

• Mouth sores
• Nausea
• Diarrhea
• Fatigue
• Rash
• Fever
• Loss of appetite
• Increased risk of infections due to immunosuppression
• Pneumonitis
• Elevated cholesterol and triglycerides

Safety Advise:

Lung  

There have been reports of lung inflammation in patients taking everolimus. Kindly speak with your Healthcare Professional.

Kidney  

Creatinine values may rise after taking everolimus, suggesting possible renal impairment. While receiving treatment, patients should have routine renal function testing. Kindly speak with your Healthcare Professional.

Liver  

Use of Evermil 10 Tablet is not recommended in patients with severe liver disease. Kindly speak with your Healthcare Professional.

Pregnancy  

Everolimus can cause harm to the fetus, leading to birth defects or fetal death. Kindly speak with your Healthcare Professional.

Breast Feeding  

Everolimus is not recommended for breastfeeding mothers, as it can pass into breast milk and may harm the nursing infant. Kindly speak with your Healthcare Professional.

Alcohol  

It is unknown if drinking alcohol with taking an Evermil 10 Tablet is safe. Kindly speak with your Healthcare Professional.

Driving  

Some patients may experience fatigue or dizziness. Be cautious when driving until you know how everolimus affects you.

Storage:

Store at room temperature, away from moisture and heat. Keep out of reach of children.

How to use this Medication?

Take this medication as directed on the prescription label, orally, along with a full glass of water. Avoid grapefruit juice and do not cut, crush, or chew the tablets. Take them consistently at the same times and discontinue only as directed by your doctor.

Your pharmacist will provide you with a unique MedGuide with every prescription and refill. Every time, make sure to carefully read this information. 

Consult your pediatrician about the usage of this medication in young patients. Precautions do apply even though this medication may be administered for some diseases in children as young as one year old.

References:

1.      Houghton PJ. Everolimus. Clinical cancer research. 2010 Mar 1;16(5):1368-72.

2.      Hasskarl J. Everolimus. Small molecules in oncology. 2018:101-23.

3.      Kirchner GI, Meier-Wiedenbach I, Manns MP. Clinical pharmacokinetics of everolimus. Clinical pharmacokinetics. 2004 Feb;43:83-95.

4.    Yao JC, Shah MH, Ito T, Bohas CL, Wolin EM, Van Cutsem E, Hobday TJ, Okusaka T, Capdevila J, De Vries EG, Tomassetti P. Everolimus for advanced pancreatic neuroendocrine tumors. New England Journal of Medicine. 2011 Feb 10;364(6):514-23.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India