Neukine 300mcg Injection (Vial)

      Neukine 300mcg Injection (Vial) contains Filgrastim that stimulates the bone marrow to produce more white blood cells that help fight infection. Neukine 300 Injection is used to increase the number of white blood cells in patients with HIV infection, severe chronic neutropenia, bone marrow transplantation, and prior to stem cell donation.

Brand Name: Neukine

Composition: Filgrastim

Mechanism of Action:

In order to promote the development, maturation, and discharge of neutrophils into the bloodstream, filgrastim attaches to and activates certain receptors on the surface of neutrophil precursor cells in the bone marrow. This assists in decreasing the likelihood of infections in those with low leukocyte counts.

Uses:

• Neutropenia Due to Chemotherapy
• Bone Marrow or Stem Cell Transplantation
• Severe Chronic Neutropenia
• Hematopoietic Stem Cell Mobilization
• HIV/AIDS-related Neutropenia

Dosage and Administration:

The dosage of Neukine depends on the patient’s body weight, the condition being treated, and the response to the therapy. It is usually administered as a subcutaneous or intravenous injection.

Side Effects:

• Bone pain
• Injection site reactions (redness, pain, swelling)
• Headache
• Fatigue
• Fever
• Splenic Rupture
• Acute Respiratory Distress Syndrome
• Capillary Leak Syndrome
• Thrombocytopenia (Low Platelet Count)

Safety Advise: 

Pregnancy  

It is unknown if neukine is safe to use while pregnant. Only if the advantages of using it during pregnancy exceed the hazards should you do so. Before using this drug, kindly speak with your healthcare provider.

Breastfeeding  

It's usually not safe to take Neukine 300mcg Injection while nursing. Kindly speak with your healthcare provider.

Driving  

Neukine side effects, including as dizziness, could make it difficult to drive. Kindly speak with your healthcare provider.

Storage:

Store in the refrigerator at 2-8°C (36-46°F). The injection should not be frozen or shaken, since this could destroy the drug.

How to use this medication:

This medication is injected subcutaneously. You will receive instructions on how to prepare and administer this medication if you receive it at home. Consult the directions for use included in the packaging of your medication. Use precisely as instructed. Take your medication on a regular basis. Never take your medication more frequently than prescribed.

It's crucial that you store your used syringes and needles in a designated sharps container. Never dispose of them in a trash can. Get a sharps container by calling your pharmacist or healthcare provider if you don't already have one.

Consult your pediatrician about the usage of this medication in children. Precautions do apply even though this medication may be administered for some diseases in children as young as one month of age.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

Frequently Asked Questions:

1. What is Neukine 300mcg Injection?
Neukine 300mcg Injection contains Filgrastim, a recombinant granulocyte-colony stimulating factor (G-CSF). It may be prescribed to stimulate the bone marrow to produce more neutrophils (a type of white blood cell), potentially reducing the risk of serious infections in patients with reduced neutrophil counts.

2. What conditions may Neukine be used for?
Neukine may be considered in clinical situations such as:
•         Chemotherapy-induced neutropenia (low white cell count following cancer treatment)
•         Support following bone marrow transplantation
•         Severe chronic neutropenia
•         Peripheral blood stem cell mobilisation prior to transplantation
Its use is determined by a specialist based on individual clinical need.

3. How does Filgrastim work?
Filgrastim is believed to bind to specific receptors on bone marrow cells, stimulating the production and release of neutrophils into the bloodstream. This may reduce the severity and duration of neutropenia in some patients, potentially lowering the risk of infection.

4. How is Neukine 300mcg administered?
It may be given as a subcutaneous (under-skin) injection or as an intravenous infusion, depending on the clinical indication. It is administered by a trained healthcare professional.

5. When is Neukine typically started after chemotherapy?
Neukine is generally started 24–72 hours after chemotherapy completion. The timing is designed to help reduce the nadir (lowest point) of neutrophil counts. The precise schedule is determined by your oncologist.

6. What are the possible side effects of Neukine?
Some patients may experience:
•         Bone pain (most commonly affecting the sternum and long bones – a frequently reported effect)
•         Headache
•         Nausea
•         Fatigue
•         Injection site reactions
Consult your oncologist or haematologist if side effects are severe or significantly affecting your quality of life.

7. Are there any serious risks associated with Neukine?
Although rare, more serious adverse events have been reported in some patients, including:
•         Spleen enlargement or rupture (splenomegaly)
•         Acute respiratory distress
•         Sickle cell crises in predisposed individuals
•         Severe allergic reactions
Prompt medical attention should be sought if any unusual or severe symptoms develop.

8. How long is the treatment course?
Duration varies by indication. For chemotherapy-induced neutropenia, Neukine is typically continued until neutrophil recovery. The precise duration and dose are determined by your oncologist.

9. Can Neukine be used in paediatric patients?
Filgrastim may be used in children for certain clinical indications. Dosing is weight-based and must be determined by a paediatric oncologist or haematologist.

10. Is Neukine available without a prescription?
No. Neukine is a prescription-only biologic injection and must be used strictly under the supervision of a qualified oncologist or haematologist.

Medical Disclaimer:
Neukine 300mcg Injection (Vial) is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.