Awabac Injection

Awabac Injection contains Aztreonam 1.5g and Avibactam 0.5g, a combination antibiotic used to treat serious bacterial infections, especially those caused by multidrug-resistant gram-negative bacteria. It is commonly prescribed for complicated urinary tract infections, intra-abdominal infections, and hospital-acquired respiratory infections.

Brand Name: Awabac

Composition: Aztreonam 1.5g + Avibactam 0.5g

Mechanism of Action

Aztreonam is a monobactam antibiotic that kills bacteria by inhibiting bacterial cell wall synthesis. Avibactam is a beta-lactamase inhibitor that protects aztreonam from degradation by certain resistant bacterial enzymes, thereby enhancing its antibacterial activity.

Uses

• Urinary Tract Infections
• Complicated Intra-abdominal Infections
• Hospital-acquired and Ventilator-associated Pneumonia
• Serious infections caused by multidrug-resistant gram-negative bacteria

Dosage and Administration

Awabac Injection is administered by the intravenous route under the supervision of a qualified healthcare professional. The exact dose and duration of treatment depend on the type and severity of the infection, kidney function, and the patient's clinical condition.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Injection site pain or redness
• Headache
• Fever
• Skin rash
• Elevated liver enzymes
• Allergic reactions
• Abdominal discomfort
• Dizziness

Safety Advice

Kidney  

Dose adjustments are required in patients with renal impairment. Kindly speak with your healthcare provider.

Liver  

Liver function tests should be monitored during prolonged treatment, especially in patients with liver disease, as etoposide can cause elevated liver enzymes. Kindly speak with your healthcare provider.

Pregnancy  

Use etoposide during pregnancy only if clearly needed and under medical supervision, as its safety during pregnancy is not fully established.  Kindly speak with your healthcare provider.

Breast Feeding  

Caution is advised during breastfeeding since the drug can pass into breast milk. Kindly speak with your healthcare provider.

Alcohol  

The safety of using Awabac injection with alcohol is unknown. Kindly speak with your healthcare provider.

Storage

Store below 25°C in a cool, dry place and protect it from direct light. Keep out of the reach of children.

How to Use This Medication?

Awabac Injection is administered by a doctor or trained nurse in a hospital or healthcare setting. It is given slowly into a vein, and the duration of treatment depends on the type of infection and the patient's response to therapy.

References

1. Bush K, Bradford PA. Beta-lactams and beta-lactamase inhibitors: an overview. Cold Spring Harb Perspect Med. 2016.
2. Livermore DM, Mushtaq S. Activity of aztreonam in combination with avibactam against resistant gram-negative bacteria. J Antimicrob Chemother.
3. Goodman & Gilman's The Pharmacological Basis of Therapeutics.
4. Katzung BG. Basic & Clinical Pharmacology.

Disclaimer

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer Details

Name: Allieva Pvt. Ltd.
Address: 14/16/1, Site 4, Sahibabad Industrial Area, Ghaziabad, Uttar Pradesh 201010, India
Country of Origin: India

Frequently Asked Questions (FAQs)

1. What is Awabac Injection used for?
Awabac Injection is an antibiotic medicine used to treat serious bacterial infections, including those caused by resistant bacteria. It should be used only as per the doctor's advice.

2. How is Awabac Injection administered?
This injection is given by a trained healthcare professional through a vein in a hospital or clinic. The dose and duration are decided as per the doctor's advice.

3. What are the common side effects of Awabac Injection?
Some patients may experience nausea, diarrhea, headache, or injection site discomfort. Inform your doctor if these effects become severe or do not improve.

4. Can I take Awabac Injection during pregnancy or breastfeeding?
This medicine should be used during pregnancy or breastfeeding only if clearly needed and as per the doctor's advice. Always discuss the benefits and risks with your healthcare provider.

5. What precautions should I follow while receiving Awabac Injection?
Complete the full course of treatment and attend all follow-up appointments as recommended. Regular monitoring may be needed as per the doctor's advice.