Sutinat 50mg Capsule

Sutinat 50mg Capsule contains Sunitinib, an oral multikinase inhibitor used primarily in the treatment of certain types of cancer, including renal cell carcinoma, gastrointestinal stromal tumors, and pancreatic neuroendocrine tumors.

Brand Name: Sutinat

Composition: Sunitinib

Mechanism of Action:

VEGFR (vascular endothelial growth factor receptor), PDGFR (platelet-derived growth factor receptor), KIT, and other receptor tyrosine kinases implicated in tumor growth and angiogenesis (the creation of new blood vessels) are among the many that sunitinib inhibits. Sunitinib aids in halting the growth and metastasis of the tumor by blocking these pathways.

Uses:

·       Metastatic Renal Cell Carcinoma

·       Gastrointestinal Cancer

·       Pancreatic Cancer

Dosage and Administration:

Taken orally with or without food. Instead of chewing or crushing the capsule, it is best to swallow it whole. Depending on adverse effects, the dosage may be changed.

 Side Effects:

·       Diarrhea

·       Nausea

·       Vomiting

·       Fever

·       Headache

·       Abdominal pain

·       Leukopenia (low white blood cell count)

·       Anemia

·       Headache

·       Dizziness

·       Fatigue

Safety Advise:

Kidney  

Patients with a history of renal impairment should use Sutinat with caution since it may cause other kidney related problems. Kindly speak with your healthcare provider.

Liver  

Patients with a history of liver disease should use Sutinat with caution since it may cause other liver related problems. Kindly speak with your healthcare provider.

Pregnancy  

Pregnant women should not take Sutinat as they may harm the fetus. Kindly speak with your healthcare provider.

Breast Feeding  

It's unknown if the Sutinat tablet affects your breast milk or if it gets into your breast milk. . Kindly speak with your healthcare provider. 

Alcohol  

It is advised that you stop drinking while using Sutinat in order to prevent unwanted side effects. Kindly speak with your healthcare provider.

Storage:

The recommended temperature range for storage is 20°C to 25°C (68°F to 77°F). Keep the container closed tightly and shield it from moisture and light.

How to use this Medication?

Take sunitinib capsules once daily, with or without food, at the same time each day. Follow your doctor’s instructions precisely, including dosing cycles for specific conditions, and do not adjust the dose without consulting them.

Do not break, chew, or crush the capsules; instead, swallow them whole. Keep the capsules closed. Depending on your sunitinib dosage, you might need to take one or more pills at a time.

Reference:

1.     Deeks ED, Keating GM. Sunitinib. Drugs. 2006 Dec;66(17):2255-66.

2.     Motzer RJ, Rini BI, Bukowski RM, Curti BD, George DJ, Hudes GR, Redman BG, Margolin KA, Merchan JR, Wilding G, Ginsberg MS. Sunitinib in patients with metastatic renal cell carcinoma. Jama. 2006 Jun 7;295(21):2516-24.

3.     Kulke MH, Lenz HJ, Meropol NJ, Posey J, Ryan DP, Picus J, Bergsland E, Stuart K, Tye L, Huang X, Li JZ. Activity of sunitinib in patients with advanced neuroendocrine tumors. Journal of Clinical Oncology. 2008 Jul 10;26(20):3403-10.

4.     Rini BI. Sunitinib. Expert opinion on pharmacotherapy. 2007 Oct 1;8(14):2359-69.

Disclaimer:

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Marketer details

Name: Natco Pharma Ltd

Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India