Durataf 25mg Tablet

Durataf 25mg Tablet contains Tenofovir Alafenamide (TAF), which is a prodrug of Tenofovir and is used basically for the treatment of chronic hepatitis B and HIV infection.

Brand Name: Durataf 

Composition: Tenofovir Alafenamide

Mechanism of Action:

The body transforms tenofovir alafenamide into tenofovir, which subsequently suppresses the reverse transcriptase enzyme. By preventing viral replication, this activity lowers the viral burden and promotes immune system recovery.

Uses:

Chronic Hepatitis B virus infection

HIV Infection

Dosage and Administration:

For chronic hepatitis B, a dosage of 25mg once daily is typically suggested. The dosage for HIV treatment may change according on the particular combination regimen that is advised.

Side Effects:

• Nausea
• Diarrhea
• Headache
• Fatigue
• Abdominal pain
• Cough
• Back Pain
• Joint Pain
• Indigestion

Safety Advise: 

Liver  

It may be essential to perform routine liver function testing, particularly for individuals with liver disease. Kindly speak with your healthcare provider.

Kidney  

It may be essential to perform routine renal function testing, particularly for individuals with renal disease. Kindly speak with your healthcare provider.

Pregnancy  

It is important to speak with your healthcare provider before using Durataf 25mg Tablet if you are pregnant or intend to become pregnant.

Breast Feeding  

The possible dangers to the newborn are not fully known, considering the fact that Durataf 25mg Tablet is excreted into human breast milk. Kindly speak with your healthcare provider.

Alcohol  

It is usually advised to stay away from drinking too much alcohol when using Durataf 25mg Tablet. Kindly speak with your healthcare provider.

Storage:

Store the tablet at room temperature, between 15°C to 30°C (59°F to 86°F). Humidity: Keep the medication in a dry place and protect it from moisture.

How to use this Medication?

Take this medication orally at the same time every day, as directed on the prescription label, along with a glass of water and food. Unless your care team advises you otherwise, take your medication as prescribed; skipping doses increases the risk of developing viral resistance.

Discuss the usage of this drug in children with your care team. Precautions do need to be taken, even though it can be administered to kids as young as 12 for specific conditions. 

Get in touch with an emergency department or poison control center right away if you believe you may have taken too much of this medication.

References:

1.      De Clercq E. Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF). Biochemical pharmacology. 2016 Nov 1;119:1-7.

2.    Ray AS, Fordyce MW, Hitchcock MJ. Tenofovir alafenamide: a novel prodrug of tenofovir for the treatment of human immunodeficiency virus. Antiviral research. 2016 Jan 1;125:63-70.

3.      Di Perri G. Tenofovir alafenamide (TAF) clinical pharmacology. Le infezioni in medicina. 2021;29(4):526.

4.      Scott LJ, Chan HL. Tenofovir alafenamide: a review in chronic hepatitis B. Drugs. 2017 Jun;77(9):1017-28.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Dr. Reddy's Laboratories

Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.

Country of origin: India

Frequently Asked Questions (FAQs):

1. What is Durataf 25mg Tablet?

Durataf 25mg contains Tenofovir Alafenamide. It may be prescribed for the management of chronic hepatitis B virus (HBV) infection, requiring strict adherence to a specialist's care plan.

2. How may Durataf work?

It is believed to interfere with viral replication enzymes, which may potentially reduce the amount of hepatitis B virus in the blood and liver.

3. What conditions may it be prescribed for?

It may be considered for the long-term management of chronic HBV in eligible patients, subject to your doctor's rigorous clinical assessment.

4. How is Durataf 25mg taken?

It is generally taken orally once a day. Adhering strictly to a consistent daily timing is vital to potentially prevent viral resistance.

5. Should it be taken with food?

It is typically recommended to be taken with food. You must adhere strictly to your doctor's dietary instructions for taking this medication.

6. What are the possible side effects?

Patients may potentially experience headache, cough, fatigue, or mild gastrointestinal upset. Report any concerning symptoms to your doctor.

7. Does it cure the infection?

No, it is a suppressive therapy. Adherence to daily dosing over a long period is usually required to maintain potential control over the virus.

8. Are there severe risks if I stop taking it?

Yes, stopping abruptly may potentially trigger a severe, acute exacerbation of hepatitis B. You must never stop taking it without adhering to your doctor's direct orders.

9. Is regular monitoring required?

Your doctor will mandate periodic blood tests to check liver function and viral load. You must attend these scheduled medical check-ups.

10. Can it be taken with other medicines?

It may potentially interact with certain anticonvulsants or antimicrobials. You must provide a complete list of your medications so your doctor can ensure safe prescribing.

11. Is it safe during pregnancy?

Use during pregnancy must be carefully evaluated by a specialist. Adhere to your obstetrician's advice regarding maternal and fetal safety.

12. Is Durataf a prescription medicine?

Yes, it is a prescription-only medicine used strictly under the supervision of a hepatologist or infectious disease specialist.

Medical Disclaimer:

Durataf 25mg Tablet is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.