Upadoz 15mg Tablet

Upadoz 15mg Tablet

Upadoz 15mg tablet: contain upadacitinib, an oral janus kinase (JAK) inhibitor primarily used for the treatment of autoimmune inflammatory disease. It helps to reduce inflammation by blocking specific enzyme involved in the immune response.

Because Upadacitinib may interact with other medicines and increase the risk of infections, blood clots, and other serious side effects, inform your doctor about all medications you are taking before starting treatment. Women who are pregnant or breastfeeding should consult their healthcare provider before use. Regular blood tests may be required during treatment to monitor blood counts, liver function, and lipid levels.

Brand Name: Upadoz 15

Composition: Upadacitinib 15mg

Mechanism of Action:

Upadacitinib is a selective Janus kinase (JAK1) inhibitor that blocks intracellular signaling pathways involved in inflammation. By inhibiting JAK1 activity, it reduces the production of inflammatory cytokines responsible for autoimmune diseases, helping relieve symptoms and prevent disease progression.

Uses:

• Rheumatoid Arthritis
• Psoriatic Arthritis
• Ankylosing Spondylitis
• Atopic Dermatitis
• Ulcerative Colitis
• Crohn's Disease

Dosage and Administration:

The dosage depends on the disease being treated and the patient's clinical condition. Upadoz 15mg is usually taken orally once daily, with or without food, exactly as prescribed by the treating physician. Swallow the tablet whole without crushing, chewing, or splitting it.

Side Effects:

• Upper respiratory tract infection
• Nausea
• Headache
• Cough
• Fever
• Acne
• Increased cholesterol levels
• Elevated liver enzymes

Kidney  

Dose adjustments are required in patients with renal impairment. Kindly speak with your healthcare provider.

Liver  

Liver function tests should be monitored during prolonged treatment, especially in patients with liver disease. Kindly speak with your healthcare provider.

Pregnancy  

Use Upadoz tablet during pregnancy only if clearly needed and under medical supervision, as its safety during pregnancy is not fully established.  Kindly speak with your healthcare provider.

Breast Feeding  

Caution is advised during breastfeeding since the drug can pass into breast milk. Kindly speak with your healthcare provider.

Driving  

Your ability to drive may be impacted by adverse effects from Upadoz Tablet. Kindly speak with your healthcare provider.

Storage:

Store Enbrel Injection in the refrigerator (30°C) and protect it from light. Keep out of the reach of children.

How to use this medication?

Take Upadoz 15mg Tablet exactly as prescribed by your doctor. Swallow the tablet whole with water and do not crush, chew, or break it. It can be taken with or without food at the same time each day.

Do not stop taking the medication without consulting your healthcare provider. Regular blood tests may be required during treatment to monitor your health and detect possible side effects early.

References:

1. Smolen JS, Pangan AL, Emery P, et al. Upadacitinib as monotherapy in patients with active rheumatoid arthritis. Lancet. 2019;393:2303-2311.
2. Burmester GR, Kremer JM, Van den Bosch F, et al. Safety and efficacy of Upadacitinib in rheumatoid arthritis. Arthritis Rheumatol. 2018.
3. Sandborn WJ, Feagan BG, Hanauer SB, et al. Upadacitinib as induction and maintenance therapy for ulcerative colitis. N Engl J Med. 2022.
4. European Medicines Agency. Upadacitinib Summary of Product Characteristics.

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Zydus Lifesciences Limited

Address: Zydus Corporate Park, Scheme No. 63, Survey No. 536, Khoraj (Gandhinagar), Sarkhej–Gandhinagar Highway, Ahmedabad – 382481, Gujarat, India.

Country of origin: India

Frequently Asked Questions (FAQs):

1. What is Upadoz 15mg Tablet?
Upadoz 15mg contains Upadacitinib, a selective Janus kinase (JAK) inhibitor that may be prescribed to potentially manage autoimmune inflammatory diseases under specialist supervision.

2. How may Upadoz work?
It is believed to selectively inhibit JAK1 enzymes involved in inflammatory signaling, potentially helping reduce pain, swelling, and disease activity.

3. What conditions may it be prescribed for?
It may be considered for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, atopic dermatitis, ulcerative colitis, and Crohn's disease, based on your doctor's diagnosis.

4. How should Upadoz 15mg Tablet be taken?
It is usually taken once daily by mouth, with or without food. Swallow the tablet whole and follow your doctor's prescribed dosing schedule.

5. What are the possible side effects?
Patients may potentially experience nausea, headache, acne, cough, upper respiratory infections, or increased cholesterol levels.

6. Does Upadoz increase the risk of infections?
Yes, because it affects the immune system, it may increase the risk of serious bacterial, viral, fungal, or opportunistic infections. Inform your doctor immediately if signs of infection develop.

7. Are blood tests required before and during treatment?
Yes, doctors generally recommend blood tests to monitor blood cell counts, liver function, cholesterol levels, and signs of infection before and during treatment.

8. Can Upadoz increase the risk of blood clots?
Rarely, serious blood clots, cardiovascular events, and certain malignancies have been reported. Patients with risk factors require careful medical evaluation before treatment.

9. Can vaccines be taken while using Upadoz?
Live vaccines should generally be avoided during treatment. Consult your healthcare provider before receiving any vaccination.

10. How should Upadoz 15mg Tablet be stored?
Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Medical Disclaimer:

Upadoz 15mg Tablet is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.