Pamorelin LA 22.5mg Injection – Uses, Price & Triptorelin for Prostate Cancer

Pamorelin LA 22.5mg Injection contains Triptorelin, a synthetic analog of gonadotropin-releasing hormone (GnRH). It reduces gonadal steroid hormones by first increasing and then suppressing the pituitary gland's production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

Brand Name: Pamorelin

Composition: Triptorelin 22.5mg

Mechanism of Action:

The pituitary gland first releases LH and FSH in response to triptorelin's stimulation (flare effect). Long-term use results in receptor downregulation and suppression of the release of LH and FSH, which lowers the amount of testosterone or estrogen produced.

Uses of Pamorelin LA 22.5mg Injection:

·        Prostate Cancer

·        Endometriosis

·        Uterine Fibroids

Dosage and Administration:

The administering route is either intramuscular or subcutaneous. The dosage varies according to the indication; adhere to the recommended schedule.

Side Effects of Pamorelin LA 22.5mg Injection:

·        Nausea

·        Vomiting

·        Fever

·        Chill

·        Dizziness

·        Diarrhea

·        Fatigue

·        Injection site reactions (pain, redness, irritation)

Contraindications/Warnings:  

As a GnRH agonist, triptorelin carries several important warnings:

(1) Tumor flare — an initial transient surge in testosterone (or estrogen) during the first weeks of therapy can temporarily worsen symptoms, and in prostate cancer patients with vertebral metastases or urinary tract obstruction, may precipitate spinal cord compression or worsened urinary obstruction, requiring close monitoring during the first month

(2) QT/QTc prolongation  long-term androgen deprivation therapy may increase this risk, so caution is advised in patients with a history of QT prolongation, electrolyte abnormalities, or on other QT-prolonging drugs

(3) Loss of bone mineral density with long-term use (see FAQ below). Contraindicated in pregnancy, in patients with known hypersensitivity to GnRH or GnRH agonist analogs, and should not be used in patients with undiagnosed abnormal vaginal bleeding.

Safety Advise:

Lungs  

The safety of Pamorelin Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Pamorelin Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Pamorelin Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Pamorelin should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using Pamorelin while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Store in a Normal Temperature. Protect from light and use immediately after reconstitution.

How to use this Medication?

A medical practitioner can inject triptorelin, a long-acting suspension, into the muscle at intervals of 4, 12, or 24 weeks, depending on the condition.

In the initial weeks following injection, triptorelin may result in a rise in specific hormones. Throughout this period, your doctor will keep a close eye on you for any new or worsening symptoms.

Frequently Asked Questions (FAQs):

1. What is Pamorelin LA 22.5mg Injection used for?

It is used as hormone therapy for advanced prostate cancer.

2. How does Pamorelin LA work?

Triptorelin initially stimulates and then suppresses GnRH signalling, lowering testosterone levels.

3. Is Pamorelin LA chemotherapy?

No. It is a GnRH agonist used as hormone therapy.

4. How often is Pamorelin LA 22.5mg given?

The 22.5mg long-acting formulation is generally administered at 6-month intervals, as prescribed.

5. Does Pamorelin LA affect bone health?

Long-term hormone suppression can reduce bone mineral density, so bone health may require monitoring.

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.
Country of origin: India