Dactolieva 0.5mg Injection

Dactolieva 0.5mg Injection contains Dactinomycin is used to treat Wilms' tumor, rhabdomyosarcoma, Ewing sarcoma, and gestational trophoblastic neoplasia.

Brand Name: Dactolieva
Composition: Dactinomycin 0.5mg

Mechanism of Action:

Dactinomycin works by binding to DNA between guanine-cytosine base pairs. This interaction blocks DNA-dependent RNA synthesis, preventing cancer cells from producing the proteins required for growth and multiplication. By interfering with essential cellular processes, Dactinomycin slows or stops the growth of cancer cells and ultimately leads to their death.

Uses:

• Wilms' Tumor
• Rhabdomyosarcoma
• Ewing Sarcoma
• Gestational Trophoblastic Neoplasia
• Testicular Cancer (in combination therapy)

Dosage and Administration:

The dosage is determined by the treating oncologist based on body weight, body surface area, type of cancer, and the patient's overall clinical condition. Dactolieva 0.5mg Injection is administered intravenously under the supervision of a qualified healthcare professional.

Side Effects:

• Nausea
• Vomiting
• Loss of appetite
• Mouth ulcers
• Fatigue
• Fever
• Low white blood cell count (Leukopenia)
• Low platelet count (Thrombocytopenia)
• Hair loss
• Injection site reactions

Safety Advice:

Lungs
The sfety of Dactolieva Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver
The safety of Dactolieva Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney
The safety of Dactolieva Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy
Dactolieva should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breastfeeding
Using Dactolieva while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:
Keep it out of direct sunlight and store it in its original container below 25°C. Keep out of children's reach. Observe the institutional policies on the handling and storage of cytotoxic medications.

How to Use This Medication?

In a hospital or oncology clinic, qualified medical personnel inject Dactolieva 0.5 mg straight into a vein. The type of cancer being treated and the patient's reaction to treatment determine the course of treatment. To track the effectiveness and safety of treatment, routine blood tests can be necessary.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer Details

Name: Allieva Pvt. Ltd.
Address: 14/16/1, Site 4, Sahibabad Industrial Area, Ghaziabad, Uttar Pradesh 201010, India
Country of Origin: India

References (Vancouver Style):

1. Brunton LL, Hilal-Dandan R, Knollmann BC. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education; 2023.
2. Katzung BG. Basic & Clinical Pharmacology. 16th ed. New York: McGraw-Hill Education; 2024.
3. National Center for Biotechnology Information. Dactinomycin. StatPearls Publishing; 2025.
4. Tan TC, Neilan TG, Francis S, Plana JC, Scherrer-Crosbie M. Anthracycline-induced cardiomyopathy and chemotherapy-related cardiac dysfunction. Heart. 2015;101(11):884-891.

Frequently Asked Questions (FAQs):

1. What is Dactolieva 0.5mg Injection used for?
Dactolieva 0.5mg Injection is used to treat several types of cancer, including Wilms' tumor, rhabdomyosarcoma, Ewing sarcoma, and gestational trophoblastic neoplasia.

2. How is Dactolieva 0.5mg Injection administered?
It is given as an intravenous injection by a trained healthcare professional in a hospital or oncology setting.

3. What are the common side effects of Dactolieva 0.5mg Injection?
Common side effects include nausea, vomiting, mouth sores, fatigue, hair loss, and temporary reductions in blood cell counts.

4. Will I need monitoring during treatment?
Yes. Regular blood tests and clinical assessments are usually required to monitor blood counts, liver function, and treatment response.

5. What precautions should I take while receiving Dactolieva 0.5mg Injection?
Inform your doctor about any existing medical conditions, ongoing medications, pregnancy status, or breastfeeding before starting treatment. Follow all medical advice and attend scheduled follow-up appointments.