Sorafekast 200mg Tablet

Sorafekast 200mg Tablet contains Sorafenib is a tyrosine kinase inhibitor used to treat liver, kidney, and thyroid cancers.

Brand Name: Sorafekast

Composition: Sorafenib 200mg 

Mechanism of Action:

A multi-kinase inhibitor called sorafenib targets many receptors implicated in angiogenesis and tumor development. It mostly prevents:

·         The receptor for the vascular endothelial growth factor

·         Growth factor receptor generated from platelets

·         A component of the MAPK/ERK signaling cascade is Raf kinase.

Sorafenib works by obstructing these pathways, which inhibits the development of tumors, reduces angiogenesis (the production of new blood vessels), and causes cancer cells to undergo programmed cell death (apoptosis).

Uses:

• Renal Cancer
• Liver Cancer
• Thyroid cancer

Side effects:

•          Diarrhea
•          Fatigue
•          Nausea
•          Vomiting
•          Skin rash or dermatitis
•          Hand-foot syndrome
•          Hypertension
•          Gastrointestinal bleeding
•          Heart failure
•      Cardiac ischemia/infarction
•      Cardiac ischemia/infarction
•      QT interval prolongation
•       Impaired wound healing
•       Gastrointestinal perforation

Dosage and Administration: 

The usual recommended dose of Sorafekast Tablet is 200mg taken twice daily, with adjustments based on tolerance and clinical response. It should be taken on an empty stomach, at least 1 hour before or 2 hours after meals, and the tablets should be swallowed whole with water without crushing or chewing.

Contraindications/Warnings: 

Sorafenib carries serious warnings for hepatotoxicity, which can be severe and, rarely, fatal; liver function should be monitored regularly, especially during the first two months of treatment. It also carries risks of hemorrhage (including fatal bleeding events), gastrointestinal perforation, hypertension (blood pressure should be monitored and controlled before starting therapy), cardiac ischemia and infarction, QT prolongation, and impaired wound healing — sorafenib should be stopped before elective surgery. It is contraindicated in patients with known hypersensitivity to sorafenib. Concurrent use with certain chemotherapy agents (such as platinum-based drugs combined with carboplatin/paclitaxel in squamous cell lung cancer) is not recommended due to increased mortality risk seen in clinical trials.

Safety advices:

Lung  

Patients with specific lung conditions should be given Sorafekast 200mg tablets with caution. Kindly speak with your healthcare provider. 

Liver  

When treating individuals with severe liver disease, Sorafekast tablets should be used cautiously. A Sorafekast tablet dosage adjustment may be necessary. Kindly speak with your healthcare provider. 

Kidney 

Sorafenib should be used with caution in patients with renal impairment; electrolyte and renal function monitoring is advised, particularly in patients at risk of renal failure. Kindly speak with your healthcare provider.

Pregnancy  

There is clear evidence that using Sorafekast tablets while pregnant poses a danger to the growing fetus and can cause fetal harm. Kindly speak with your healthcare provider. 

Breast feeding  

It is not recommended to use Sorafekast Tablets during nursing. Evidence points to the possibility of medication  harmful to the infant. Kindly speak with your healthcare provider. 

Alcohol  

It is unknown if drinking alcohol while taking Sorafekast Tablets is safe. Kindly speak with your healthcare provider. 

Storage:

Keep the product at room temperature; the recommended range is 20°C to 25°. Store away from moisture and in a dry environment. Keep out of direct sunlight and keep in original packaging. Keep out of children grasp

How to use this Medication?  

Do not cut, crush, or chew the tablet; instead, take this medication by mouth with a glass of water on an empty stomach, at least one hour before or two hours after meals. When using it on children, be sure to check with your physician, adhere to the prescription's directions, and take the medication as directed on a regular basis. Get in touch with emergency services or a poison control center right once if you suspect an overdose.

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer Details:

Name: Aprazer Healthcare Pvt Ltd
Address: 16/13, GROUND FLOOR, OLD RAJINDER NAGAR, NEW DELHI Central Delhi DL IN 110060.
Country of Origin: India