Urotone 25 mg Tablet contains Bethanechol Chloride, a direct-acting cholinergic (muscarinic) agonist that stimulates the smooth muscles of the urinary bladder. It is used to treat non-obstructive urinary retention, particularly after surgery, childbirth, or in patients with neurogenic bladder disorders. By increasing bladder muscle contractions, it helps improve bladder emptying and relieves difficulty in urination.

Before starting treatment, inform your doctor if you have asthma, peptic ulcer disease, epilepsy, hyperthyroidism, Parkinson's disease, low blood pressure, coronary artery disease, or gastrointestinal or urinary tract obstruction. This medication should not be used during pregnancy or breastfeeding unless specifically recommended by your healthcare provider. Regular clinical monitoring is advised to assess therapeutic response and minimize the risk of adverse effects.

Brand Name: Urotone

Composition: Bethanechol Chloride 25 mg

Mechanism of Action:

Bethanechol Chloride is a direct-acting parasympathomimetic agent that selectively stimulates muscarinic receptors. It increases the tone and contractility of the detrusor muscle of the urinary bladder while relaxing the bladder trigone and sphincter, facilitating bladder emptying. Bethanechol has minimal effects on nicotinic receptors and primarily acts on smooth muscles of the urinary and gastrointestinal tracts.

Uses:

• Non-obstructive urinary retention
• Postoperative urinary retention
• Postpartum urinary retention
• Neurogenic bladder with urinary retention

Dosage and Administration:

Urotone 25 mg Tablet should be taken only under the supervision of a qualified healthcare professional. The dosage and duration of treatment depend on the patient's age, medical condition, and response to therapy.

The tablet is usually taken on an empty stomach, preferably 1 hour before or 2 hours after meals, to reduce the risk of nausea and vomiting. Follow your doctor's instructions carefully and do not exceed the prescribed dose. Your healthcare provider may adjust the dosage according to your clinical response.

Side Effects:

• Nausea
• Vomiting
• Abdominal cramps
• Diarrhea
• Increased salivation
• Sweating
• Headache
• Dizziness
• Low blood pressure (Hypotension)
• Increased urge to urinate
• Bronchospasm (rare)

Safety Advice:

Kidney  

Patients with a history of renal impairment should use Bethanechol Chloride with caution since it may cause other kidney related problems. Kindly speak with your healthcare provider.

Liver  

Patients with a history of liver disease should use Bethanechol Chloride with caution since it may cause other liver related problems. Kindly speak with your healthcare provider.

Pregnancy  

Pregnant women should not take Bethanechol Chloride as they may harm the fetus. Kindly speak with your healthcare provider.

Breast Feeding  

It's unknown if the Bethanechol Chloride tablet affects your breast milk or if it gets into your breast milk.  Kindly speak with your healthcare provider. 

Alcohol  

It is advised that you stop drinking while using Bethanechol Chloride in order to prevent unwanted side effects. Kindly speak with your healthcare provider.

How to Use this Medication?

Take Urotone 25 mg Tablet exactly as prescribed by your doctor. It is generally recommended to take the tablet on an empty stomach, either one hour before or two hours after meals, with a glass of water.

Do not crush, chew, or break the tablet unless advised by your healthcare provider. Continue taking the medicine for the full prescribed duration even if your symptoms improve. Do not discontinue treatment without consulting your doctor.

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.

References:

1. Brunton LL, Hilal-Dandan R, Knollmann BC, editors. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 14th Edition. McGraw-Hill Education; 2022.
2. Katzung BG, Vanderah TW. Basic & Clinical Pharmacology. 16th Edition. McGraw-Hill Education; 2024.
3. Brunton LL, Hilal-Dandan R, Knollmann BC. Goodman & Gilman's Manual of Pharmacology and Therapeutics. McGraw-Hill Education.
4. AHFS Drug Information. Bethanechol Chloride Monograph. American Society of Health-System Pharmacists.

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer Details

Name: Samarth Life Sciences Pvt. Ltd.
Address: 208, 2nd Floor, Bhanot Corner, Pamposh Enclave, Greater Kailash-I, New Delhi – 110048, India.
Country of Origin: India

Frequently Asked Questions (FAQs)

1. What is Urotone 25 mg Tablet?

Urotone 25 mg Tablet contains Bethanechol Chloride, a cholinergic agonist used to treat non-obstructive urinary retention by improving bladder muscle contractions and facilitating urination.

2. How does Bethanechol Chloride work?

Bethanechol stimulates muscarinic receptors in the urinary bladder, increasing detrusor muscle contraction and promoting bladder emptying.

3. What conditions is Urotone prescribed for?

It is prescribed for postoperative urinary retention, postpartum urinary retention, neurogenic bladder, and other forms of non-obstructive urinary retention.

4. How should Urotone 25 mg Tablet be taken?

Take the tablet exactly as prescribed by your doctor, preferably on an empty stomach, one hour before or two hours after meals.

5. What are the common side effects of Bethanechol?

Common side effects include nausea, vomiting, abdominal cramps, diarrhea, sweating, flushing, headache, dizziness, increased salivation, and frequent urination.

6. Can Urotone be used during pregnancy?

Bethanechol should only be used during pregnancy if the potential benefit outweighs the possible risk to the fetus. Consult your healthcare provider before use.

7. Is Urotone safe during breastfeeding?

It is not known whether Bethanechol passes into human breast milk. Breastfeeding mothers should seek medical advice before taking this medication.

8. Can I consume alcohol while taking Urotone?

Alcohol may increase dizziness or low blood pressure in some individuals. It is advisable to avoid or limit alcohol consumption while taking Bethanechol.

9. What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses together.

10. Who should not take Urotone?

Bethanechol should not be used in patients with urinary tract obstruction, gastrointestinal obstruction, peptic ulcer disease, uncontrolled asthma, hyperthyroidism, epilepsy, severe hypotension, or bradycardia unless specifically advised by a healthcare professional.