Cabdual 40mg Tablet

Cabdual 40mg Tablet – Uses, Price & Kidney Cancer Treatment

Cabdual 40mg Tablet contains Cabozantinib as its active ingredient. By blocking many receptor tyrosine kinases (RTKs) involved in tumor growth, metastasis, and angiogenesis, the tyrosine kinase inhibitor (TKI) cabotinib is used to treat a variety of cancer types.

Brand Name: Cabdual

Composition: Cabozantinib

Mechanism of Action:

Multiple tyrosine kinases, such as MET, VEGFR, and RET, which are implicated in several pathways essential for tumor cell development and angiogenesis (blood vessel creation), are inhibited by cabotinib. Cabozantinib can decrease the blood supply to tumors and impede the growth and spread of cancer cells by blocking these kinases.

Uses:

·       Liver Cancer

·       Kidney Cancer

·       Medullary thyroid Cancer

Dosage and Administration:

Depending on the type of cancer being treated and patient characteristics like liver or renal function, the usual dosage for Cabdual is 40mg once daily. It must be taken at least two hours before or after a meal, on an empty stomach.

Side Effects:

·       Diarrhea

·       Fatigue

·       Nausea

·       Vomiting

·       Anemia

·       Decreased appetite

·       Weight loss

·       Elevated liver enzymes

·       Hypertension (high blood pressure)

·       Palmar-plantar erythrodysesthesia (hand-foot syndrome)

Safety Advise:

Liver  

For patients with liver issues, dose modifications might be necessary, and routine liver function monitoring is advised. Kindly speak with your healthcare provider.

Kidney  

For patients with kidney issues, dose modifications might be necessary, and routine renal function monitoring is advised. Kindly speak with your healthcare provider.

Pregnancy  

Cabozantinib is not advised during pregnancy since it may harm the fetus. Kindly speak with your healthcare provider.

Breast Feeding  

Cabdual 40mg Tablet is probably unsafe to use during breastfeeding. Kindly speak with your healthcare provider.

Alcohol  

The safety of combining alcohol with Cabdual 40mg Tablet is unknown. Kindly speak with your healthcare provider.

Storage:

Store at room temperature between 15°C and 30°C (59°F and 86°F). Keep in a dry place, protected from direct light and moisture.

How to use this Medication?

Cabozantinib is a pill that is typically given once a day, either one hour before or two hours after meals, on an empty stomach. Pay close attention to what your doctor tells you, and don't change the dosage without consulting your doctor.

Drink a full glass of water and swallow the tablets whole. Avoid opening, crushing, chewing, and splitting them.

References:

1.     Lacy SA, Miles DR, Nguyen LT. Clinical pharmacokinetics and pharmacodynamics of cabozantinib. Clinical pharmacokinetics. 4017 May;56:477-91.

2.     Abou-Alfa GK, Meyer T, Cheng AL, El-Khoueiry AB, Rimassa L, Ryoo BY, Cicin I, Merle P, Chen Y, Park JW, Blanc JF. Cabozantinib in patients with advanced and progressing hepatocellular carcinoma. New England Journal of Medicine. 4018 Jul 5;379(1):54-63.

3.     Maroto P, Porta C, Capdevila J, Apolo AB, Viteri S, Rodriguez-Antona C, Martin L, Castellano D. Cabozantinib for the treatment of solid tumors: a systematic review. Therapeutic advances in medical oncology. 4022 Jun;14:17588359221107112.

4.     Fallahi P, M Ferrari S, Di Bari F, Materazzi G, Benvenga S, Miccoli P, Antonelli A. Cabozantinib in thyroid cancer. Recent Patents on Anti-Cancer Drug Discovery. 4015 Sep 1;10(3):259-69.

FAQs for Cabdual 40mg Tablet

What is Cabdual 40mg Tablet used for?

It is used to treat advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer) and differentiated thyroid cancer.

How does Cabdual 40mg Tablet work?

It blocks multiple tyrosine kinase receptors including VEGFR and MET, reducing tumour growth and blood vessel formation.

Is Cabdual a chemotherapy medicine?

No. It is a targeted therapy medicine belonging to the tyrosine kinase inhibitor (TKI) class.

What is Cabozantinib?

Cabozantinib is a targeted anticancer medicine that blocks proteins responsible for tumour growth, angiogenesis and metastasis.

Is Cabdual used for kidney cancer?

Yes. It is widely prescribed for advanced renal cell carcinoma (RCC).

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details:

Name: Intas
Address: Intas Pharmaceuticals Ltd. Plot No. 457-458, Village: Matoda, tal.Sanand, Dist, Ahmedabad – 382210, Gujarat, India
Country of origin: India